Protein Alignment STK4 and stk3

DIOPT Version :10

• Sequence 1: NP_006273.1
• Gene: STK4 / 6789
• HGNCID: 11408
• Length: 487
• Species: Homo sapiens
• Sequence 2: NP_955966.1
• Gene: stk3 / 324125
• ZFINID: ZDB-GENE-030131-2845
• Length: 492
• Species: Danio rerio
• Alignment Length: 487
• Identity: 375/487 - (77%)
• Similarity: 425/487 - (87%)
• Gaps: 9/487 - (1%)

Human    10 PRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEIIKEI 74
            |:.:||||.||||||||||||||||||||||||||:||||||:||:|||||||||||||||||||
Zfish     6 PKNKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEI 70

Human    75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEY 139
            |||||||||:||||||||||||||||||||||||||||||||||||||||||||:|:||||||||
Zfish    71 SIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLKSTLKGLEY 135

Human   140 LHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCV 204
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   136 LHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCV 200

Human   205 ADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQR 269
            |||||||||:||||||||||||||||||||||||||||||||||.|||:||||||:||||:||||
Zfish   201 ADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPEHWSDDFTDFVKKCLVKNPEQR 265

Human   270 ATATQLLQHPFVRSAKGVSILRDLINEAMDVKLKRQESQQREVDQDDEENSEEDEMDSGTMVRAV 334
            |||||||||||:..||.||||||||.||||:|.|||:.||||:::|||.:.||.|:||.|||::.
Zfish   266 ATATQLLQHPFIVGAKPVSILRDLITEAMDMKAKRQQEQQRELEEDDENSEEEVEVDSHTMVKSG 330

Human   335 GDEMGTVRVASTMTDGANTMIEHDDT-LPSQLGTMVINAEDEEEE---GTMKRRDETMQPAKPSF 395
            .:..||:|...||:|||.|||||..| |.|.|||||||::|||||   |:|:|...:.|..:|||
Zfish   331 SESAGTMRATGTMSDGAQTMIEHGSTMLESNLGTMVINSDDEEEEEDLGSMRRNPTSQQIQRPSF 395

Human   396 LEYFEQKEKENQINSFGKSVPGPLKNS-----SDWKIPQDGDYEFLKSWTVEDLQKRLLALDPMM 455
            ::||::::.......|..:...|...|     .:||:|||||::|||:...|:||.||.||||||
Zfish   396 MDYFDKQDSNKAQEGFNHNQQDPCLISKTAFPDNWKVPQDGDFDFLKNLDFEELQMRLTALDPMM 460

Human   456 EQEIEEIRQKYQSKRQPILDAIEAKKRRQQNF 487
            |:||||:||:|.:||||||||::|||||||||
Zfish   461 EREIEELRQRYTAKRQPILDAMDAKKRRQQNF 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STK4	NP_006273.1	STKc_MST1_2	26..281	CDD:132943	243/254 (96%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..332		17/28 (61%)
		SARAH_MST1	432..480	CDD:439181	31/47 (66%)
stk3	NP_955966.1	STKc_MST1_2	22..277	CDD:132943	243/254 (96%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..339		21/41 (51%)
		SARAH_MST2	437..485	CDD:439182	31/47 (66%)