Protein Alignment STK4 and sid1

DIOPT Version :10

• Sequence 1: NP_006273.1
• Gene: STK4 / 6789
• HGNCID: 11408
• Length: 487
• Species: Homo sapiens
• Sequence 2: NP_593564.1
• Gene: sid1 / 2542746
• PomBaseID: SPAC9G1.09
• Length: 471
• Species: Schizosaccharomyces pombe
• Alignment Length: 515
• Identity: 177/515 - (34%)
• Similarity: 260/515 - (50%)
• Gaps: 111/515 - (21%)

Human    30 FDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVES---DLQEIIKEISIMQQCDSPHVVKYYGS 91
            :.:|.|||.||:|.|:||....:|.|:||||:.:|:   |:.:|.:|:.::..|:|.:|::|||.
pombe     9 YTLLRKLGSGSFGVVWKARENVSGDIIAIKQIDLETGIDDITDIEQEVFMLSNCNSSNVIQYYGC 73

Human    92 YFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNIL 156
            :.....|||:||:...||||.::::..  |.|..|:.||:..|.||.|||...||||||||.|||
pombe    74 FVDGYTLWILMEHMDGGSVSGLLKMGR--LNEQVISIILREVLYGLNYLHGQNKIHRDIKAANIL 136

Human   157 LNTE-GHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEG 220
            |::. |:.||||||||.||::..::|:|.:||||||||||||:..|...||||||||||||||.|
pombe   137 LSSSTGNVKLADFGVAAQLSNAASRRHTFVGTPFWMAPEVIQQTSYGLAADIWSLGITAIEMANG 201

Human   221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSAK 285
            .||.|.:||||.||.||.:.||  :..:.:|..|.|||..||..:|..|.:|.:||||||::||.
pombe   202 IPPRATMHPMRVIFEIPQSEPP--KLDDHFSPTFRDFVSCCLDLNPNMRWSAKELLQHPFIKSAG 264

Human   286 GV--------------------SILRDLINEAMDVKLKRQESQQREVDQDDEENSEEDEMDSGTM 330
            .|                    |:|.:.||..    ||..|....|.:.|.|:.:.|
pombe   265 TVKDIIPLLVQKENKLFDDSDQSVLEETINNT----LKPFEEPIAEGNADIEDWTFE-------- 317

Human   331 VRAVGDEMGTVRVASTMTDGANTMIEHDDTLPSQLGTMVINAEDEEEEGTMKRRDETMQPAKPSF 395
                     ||:.:.:...| ||.|..:.         :|:::::||              .||.
pombe   318 ---------TVKKSDSTVLG-NTSIPKNS---------IISSQNKEE--------------LPSS 349

Human   396 LEYFEQKEKENQI--NSFGKSVPGPLKNSSDWKIPQDGDY---EFLKSW---------------- 439
            ::|.|:....:|.  :.|.||:.   :..|.:......|:   .::||.
pombe   350 IKYLEKTIMSDQATPHPFSKSLS---EKGSSYHKSLTSDFAMKHYIKSTIRSMLLNDKLSATQRS 411

Human   440 TVEDLQKRLLALDPMMEQEI-------EEIRQKYQSKRQPILDAI------EAKKRRQQN 486
            ::|......::||..:..:.       ..:..|.| ||.||...:      |.:|||..|
pombe   412 SLESFYTSFISLDKNLSSKFVNQITPDNRLHHKKQ-KRSPISQLLFSRWLEETEKRRSLN 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STK4	NP_006273.1	STKc_MST1_2	26..281	CDD:132943	127/254 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..332		6/28 (21%)
		SARAH_MST1	432..480	CDD:439181	13/79 (16%)
sid1	NP_593564.1	STKc_MST3_like	7..279	CDD:270786	131/273 (48%)