Protein Alignment STK4 and ppk11

DIOPT Version :10

• Sequence 1: NP_006273.1
• Gene: STK4 / 6789
• HGNCID: 11408
• Length: 487
• Species: Homo sapiens
• Sequence 2: NP_594517.1
• Gene: ppk11 / 2541473
• PomBaseID: SPAC2C4.14C
• Length: 312
• Species: Schizosaccharomyces pombe
• Alignment Length: 313
• Identity: 127/313 - (40%)
• Similarity: 192/313 - (61%)
• Gaps: 13/313 - (4%)

Human    33 LEKLGEGSYGSVYKAIHKETGQIVAIKQVPVES---DLQEIIKEISIMQQCDSPHVVKYYGSYFK 94
            |:.:|:||:|||::|...|:.:|||:|.|.:::   .::.:.:||:.:...:|.|:.|||.|:..
pombe     9 LQLIGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQIETLTQEINFLIDLNSVHITKYYASFVD 73

Human    95 NTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNT 159
            ...|||.||||..||..|:::| :.|.:|..||.:::..|:.|.|||...|:||||||.|||...
pombe    74 GFRLWITMEYCDGGSCLDLLKL-SGTFSERVIAEVMRQVLEALVYLHGQGKMHRDIKAANILTMK 137

Human   160 EGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPY 224
            :|..|||||||:|||.....|.:..:||||||||||:::.|||..||||||||||.|:|.|:|||
pombe   138 DGLVKLADFGVSGQLESLRDKNDDFVGTPFWMAPEVVKQTGYNYKADIWSLGITAYELATGEPPY 202

Human   225 ADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSAKGVSI 289
            :.||||:.:.:||.:.||:..:.: :|..|.|||..||.|:|:.||||..|.:|.|::.....:.
pombe   203 SGIHPMKVLLLIPKHSPPSLERSK-FSRAFCDFVSNCLKKNPKDRATAEYLSKHKFIKKYCPNTS 266

Human   290 LRDLINEAMDVKLKRQESQQREVDQDDEENSEEDEMDSGTMVRAVGDEMGTVR 342
            :::::  |...|.|..|........:....:..:.:|.      |..:.||||
pombe   267 VKEVV--ASYAKWKESELLPEATPYNSTMGNSANTIDE------VVWDFGTVR 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STK4	NP_006273.1	STKc_MST1_2	26..281	CDD:132943	116/250 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..332		3/28 (11%)
		SARAH_MST1	432..480	CDD:439181
ppk11	NP_594517.1	STKc_MST3_like	4..278	CDD:270786	119/272 (44%)