Protein Alignment STK3 and SPS1

DIOPT Version :10

• Sequence 1: XP_016869245.1
• Gene: STK3 / 6788
• HGNCID: 11406
• Length: 580
• Species: Homo sapiens
• Sequence 2: NP_010811.1
• Gene: SPS1 / 852135
• SGDID: S000002931
• Length: 490
• Species: Saccharomyces cerevisiae
• Alignment Length: 407
• Identity: 140/407 - (34%)
• Similarity: 219/407 - (53%)
• Gaps: 44/407 - (10%)

Human    97 KKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVE---SDLQEIIKEISI 158
            |::|..|.| .|.:::.:...:|.|::|.|:||:.:.:.::||||.|.:|   .|::.:.:||..
Yeast     4 KEISIRSRT-PPSKLYSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFF 67

Human   159 MQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDII-RLRNKTLIEDEIATILKSTLKGLEYL 222
            :.:..||.:..|..:..::..:||||||||.||.||:: |.....|.|::::.|:.....||:||
Yeast    68 LAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYL 132

Human   223 HFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI--QEIGYNC 285
            |..|||||||||.|||||.||..||.||||:|.:..|: ||:|.:|||:||||||:  :..|||.
Yeast   133 HEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTL-KRDTFVGTPYWMAPEVVCCEVDGYNE 196

Human   286 VADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQ 350
            .|||||||||:.|:.:|.||.:...||:.:..:|...||..:.|  :||...|||..||||.|..
Yeast   197 KADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGP--FSDAAKDFVAGCLVKTPAD 259

Human   351 RATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKRHEEQQRELE-----------------EEE 398
            |.:|..||...|:||.    .:.:|.::...||.|:.:|:..::.                 :|.
Yeast   260 RPSAYNLLSFEFVKNI----TITNLKSDVDLIKQKKVQERYTKVPKYPLQNRLYKNSNTVRGKEF 320

Human   399 ENSDEDELDSHTMVKTSVESVGTMRATSTMSEGAQTMIEHNSTMLESDLGTMVINSEDEEEEDGT 463
            .|.:...|.:..:.|..:..:.....||:::..:..:: |..|:      |.:.|      ...:
Yeast   321 WNFESTRLSTTQISKEELSPITQDSPTSSLNMESPYLL-HGQTV------TPITN------PSSS 372

Human   464 MKRNATSPQVQRPSFMD 480
            ..|..|.|..:..|.||
Yeast   373 SFRKCTQPVFELDSGMD 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STK3	XP_016869245.1	STKc_MST1_2	108..363	CDD:132943	112/260 (43%)
SPS1	NP_010811.1	STKc_MST3_like	16..291	CDD:270786	117/281 (42%)