Protein Alignment STK3 and mbt

DIOPT Version :10

• Sequence 1: XP_016869245.1
• Gene: STK3 / 6788
• HGNCID: 11406
• Length: 580
• Species: Homo sapiens
• Sequence 2: NP_523375.2
• Gene: mbt / 32631
• FlyBaseID: FBgn0025743
• Length: 639
• Species: Drosophila melanogaster
• Alignment Length: 325
• Identity: 122/325 - (37%)
• Similarity: 185/325 - (56%)
• Gaps: 18/325 - (5%)

Human    73 GAASVFKKKEWSTQGE--ENKQDSKL------KKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKA 129
            ||:|..::...::.|.  :.|||.:|      ..|........|.|..|...|:||||.|:|..|
  Fly   321 GASSAAQQASGASGGAAGQPKQDQRLTHEQFRAALQMVVSAGDPRENLDHFNKIGEGSTGTVCIA 385

Human   130 IHKESGQVVAIKQVPVESDLQE--IIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSV 192
            ..|.:|:.||:|::.:....:.  :..|:.||:....|.:|:.|.|:..|.:||:||||...|::
  Fly   386 TDKSTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYHHPNIVETYSSFLVNDELWVVMEYLEGGAL 450

Human   193 SDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLT 257
            :||:  .:..:.|::|||:.|..||.|.|||....||||||:.:|||..:|..||:|||...|::
  Fly   451 TDIV--THSRMDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSILLAADGRVKLSDFGFCAQVS 513

Human   258 DTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNP 322
            ..:.||.:::|||:||:||||..:.|....|||||||..|||.:|:||:.:..|::|:..|....
  Fly   514 QELPKRKSLVGTPYWMSPEVISRLPYGPEVDIWSLGIMVIEMVDGEPPFFNEPPLQAMRRIRDMQ 578

Human   323 PPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKRH 387
            ||..:.....|.....|:.:.||::|.|||||.:||.|||::.|.|.|:|..|:..|      ||
  Fly   579 PPNLKNAHKVSPRLQSFLDRMLVRDPAQRATAAELLAHPFLRQAGPPSLLVPLMRNA------RH 637

Human   388  387
              Fly   638  637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STK3	XP_016869245.1	STKc_MST1_2	108..363	CDD:132943	104/256 (41%)
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	360..620	CDD:270815	105/261 (40%)