Protein Alignment NEK4 and KIN3

DIOPT Version :9

• Sequence 1: XP_016862574.1
• Gene: NEK4 / 6787
• HGNCID: 11399
• Length: 870
• Species: Homo sapiens
• Sequence 2: NP_009410.1
• Gene: KIN3 / 851273
• SGDID: S000000071
• Length: 435
• Species: Saccharomyces cerevisiae
• Alignment Length: 349
• Identity: 106/349 - (30%)
• Similarity: 164/349 - (46%)
• Gaps: 68/349 - (19%)

Human     2 PLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNIV 66
            |.:.|..|..:|:||:|.|..|.|....|..|.|.:...:.:|:||:....|..:||||||.|||
Yeast    21 PRSEYQVLEEIGRGSFGSVRKVIHIPTKKLLVRKDIKYGHMNSKERQQLIAECSILSQLKHENIV 85

Human    67 TYKESWEGGD--GLLYIVMGFCEGGDLYRKLK--EQKGQLLPENQVVEWFVQIAMALQYLH---- 123
            .: .:|:..:  .:||:.|.:|..|||.:.:|  :|:.:.:||..|.....|:..||...|
Yeast    86 EF-YNWDFDEQKEVLYLYMEYCSRGDLSQMIKHYKQEHKYIPEKIVWGILAQLLTALYKCHYGVE 149

Human   124 -----------------EKHILHRDLKTQNVFLT--------------------------RTN-- 143
                             :..::|||||..|:||:                          |.|
Yeast   150 LPTLTTIYDRMKPPVKGKNIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSG 214

Human   144 -----------IIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSNKPYNYKSDVWALGCCVY 197
                       ::|:||.|:|:.||.....|:|.:|||||||||:..::||:..||:|:|||.::
Yeast   215 KRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIF 279

Human   198 EMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRTMLSKRPEERPSVRSILRQPYIK 262
            ||.:|...|.||:...|..:|..||...:|..||..|..:|.:|:......|||...:|:...|:
Yeast   280 EMCSLHPPFQAKNYLELQTKIKNGKCDTVPEYYSRGLNAIIHSMIDVNLRTRPSTFELLQDIQIR 344

Human   263 -RQISFFLE--ATKIKTSKNNIKN 283
             .:.|..||  ..|:...:|.:.|
Yeast   345 TARKSLQLERFERKLLDYENELTN 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NEK4	XP_016862574.1	None
KIN3	NP_009410.1	STKc_Nek2	24..343	CDD:270857	98/319 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910