Protein Alignment NEK4 and wee1

DIOPT Version :9

• Sequence 1: XP_016862574.1
• Gene: NEK4 / 6787
• HGNCID: 11399
• Length: 870
• Species: Homo sapiens
• Sequence 2: NP_587933.1
• Gene: wee1 / 2539123
• PomBaseID: SPCC18B5.03
• Length: 877
• Species: Schizosaccharomyces pombe
• Alignment Length: 288
• Identity: 87/288 - (30%)
• Similarity: 137/288 - (47%)
• Gaps: 49/288 - (17%)

Human     3 LAAYCYLRVVGKGSYGEVTLVKHRRDGK-QYVIKKLNLRNASSRERRAAEQEAQLLSQLK-HPNI 65
            |..:..:.::|.|.:.||..|:...:.. :|.:|||.::.:..:||....||..:...|| |.:|
pombe   563 LTRFRNVTLLGSGEFSEVFQVEDPVEKTLKYAVKKLKVKFSGPKERNRLLQEVSIQRALKGHDHI 627

Human    66 VTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQL--LPENQVVEWFVQIAMALQYLHEKHIL 128
            |...:|||.| |.||:.:..||.|.|.|.|:|| |||  |.|.:|.:..|::|:.||::|.|:.:
pombe   628 VELMDSWEHG-GFLYMQVELCENGSLDRFLEEQ-GQLSRLDEFRVWKILVEVALGLQFIHHKNYV 690

Human   129 HRDLKTQNVFLTRTNIIKVGDLGIARV--------LENHCDMASTLIGTPYYMSPELFSNKPYNY 185
            |.|||..||.:|....:|:||.|:|.|        .|..|:          |::||:.:|..|:.
pombe   691 HLDLKPANVMITFEGTLKIGDFGMASVWPVPRGMEREGDCE----------YIAPEVLANHLYDK 745

Human   186 KSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPE----------------- 233
            .:|:::||..|:|.|.   .....|......::..|.|...||..|.:
pombe   746 PADIFSLGITVFEAAA---NIVLPDNGQSWQKLRSGDLSDAPRLSSTDNGSSLTSSSRETPANSI 807

Human   234 -----LAELIRTMLSKRPEERPSVRSIL 256
                 |..::..|||..|..||::..||
pombe   808 IGQGGLDRVVEWMLSPEPRNRPTIDQIL 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NEK4	XP_016862574.1	None
wee1	NP_587933.1	PTKc_Wee1_fungi	565..838	CDD:270954	86/286 (30%)
		Pkinase	566..836	CDD:278497	86/285 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910