DRSC/TRiP Functional Genomics Resources

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Protein Alignment STIM1 and Stim1

DIOPT Version :10

Sequence 1:NP_001264890.1 Gene:STIM1 / 6786 HGNCID:11386 Length:791 Species:Homo sapiens
Sequence 2:NP_001387486.1 Gene:Stim1 / 20866 MGIID:107476 Length:793 Species:Mus musculus


Alignment Length:83 Identity:21/83 - (25%)
Similarity:32/83 - (38%) Gaps:17/83 - (20%)


- Green bases have known domain annotations that are detailed below.


Human   597 ADVNRPPG--STVYTCMLNQRGGTESDLTVSR----LAPGTQASPLVPAFEGDCYYLAVGGAVAQ 655
            :|:.|||.  |...:|::     |.:.|..||    :.|...|...|..|.|.|      |::..
Mouse    36 SDMTRPPEKLSVSQSCVI-----TATGLIWSRYCLVIIPKNWALFAVNFFLGMC------GSIQL 89

Human   656 HNWSHINTVLQDQEFRCQ 673
            ......|..|:.:|...|
Mouse    90 FRIWRYNQELKQKEAEVQ 107

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
STIM1NP_001264890.1 SAM_STIM1 128..201 CDD:188972
DR0291 244..>427 CDD:441187
SOAR 342..441 CDD:465164
SOAR/CAD. /evidence=ECO:0000269|PubMed:19182790 344..442
Contributes to fast Ca(2+)-dependent inactivation of CRAC channels. /evidence=ECO:0000269|PubMed:19706554 475..483
Stim1NP_001387486.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 24..43 3/6 (50%)
SAM_STIM1 128..201 CDD:188972
Smc <251..>337 CDD:440809
SOAR 342..441 CDD:465164
SOAR/CAD. /evidence=ECO:0000250|UniProtKB:Q13586 344..442
Contributes to fast Ca(2+)-dependent inactivation of CRAC channels. /evidence=ECO:0000250|UniProtKB:Q13586 475..483
Blue background indicates that the domain is not in the aligned region.

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