DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment f9b and flz

DIOPT Version :9

Sequence 1:	NP_001035400.1	Gene:	f9b / 678552	ZFINID:	ZDB-GENE-060421-7346	Length:	507	Species:	Danio rerio
Sequence 2:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster

Alignment Length:	366	Identity:	115/366 - (31%)
Similarity:	176/366 - (48%)	Gaps:	66/366 - (18%)

- Green bases have known domain annotations that are detailed below.

Zfish   169 PRGQYPCGRLGKIIAQTLNSRAL---------ESTETVNQNQTISHI------------NGTE-Y 211
            |..:.|..|:...:..|..|.|.         |..|.||.|.:.:.|            ||.: :
  Fly  1354 PATKKPTRRVSSTVKTTTVSSARPADDEIVDEEDEEDVNPNPSDNEIDQGATLSSYGGANGRKIH 1418

Zfish   212 NTTESSPTDLSEMNSTSTPRNSLQNVSSSPILTNINNTTNNKYRIVGGDEAIPGEIPWQVVFLEK 276
            :|:.:.||.....:|.||......:|.|.              |||||..:..|..||||:..|.
  Fly  1419 STSRTLPTPNLAFHSPSTECGVRPHVKSG--------------RIVGGKGSTFGAYPWQVLVRES 1469

Zfish   277 V-------NKIVFCGGSLLSEEWVITAAHCVEGKQGSFFIRVGEHDVS-KMEGTES-DHGIEEYH 332
            .       ||   |||.|::..:|||||||..|...|....:||.|:| .:|...| ...::...
  Fly  1470 TWLGLFTKNK---CGGVLITSRYVITAAHCQPGFLASLVAVMGEFDISGDLESKRSVTKNVKRVI 1531

Zfish   333 IHPRYNSQRSLYNHDIALLKLKKPVILFDYAVPICLGS--KDFTENLLQSAENSLVSGWGRLRYG 395
            :|.:|:.  :.:.:|:|||:|..||....:.||||:.:  .|||..:      :.|:|||||:||
  Fly  1532 VHRQYDP--ATFENDLALLELDSPVQFDTHIVPICMPNDVADFTGRM------ATVTGWGRLKYG 1588

Zfish   396 GIESNVLQKVELPYVDRIKCK------GSSTDSISRFMFCAGYSTVRKDACQGDSGGPHATRYKD 454
            |...:|||:|::|.::...|:      |.:...::.|: ||||:..:||:|:||||||...:..|
  Fly  1589 GGVPSVLQEVQVPIIENSVCQEMFHTAGHNKKILTSFL-CAGYANGQKDSCEGDSGGPLVLQRPD 1652

Zfish   455 -TWFLTGIVSWGEECAKEGKYGIYTRISKYMAWITNITRIR 494
             .:.|.|.||.|.:||.....|:|.|.:.|..|:.:||.::
  Fly  1653 GRYELAGTVSHGIKCAAPYLPGVYMRTTFYKPWLRSITGVK 1693

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
f9b	NP_001035400.1	GLA	23..86	CDD:214503
		EGF_CA	88..124	CDD:238011
		FXa_inhibition	131..167	CDD:291342
		Tryp_SPc	255..487	CDD:214473	90/249 (36%)
		Tryp_SPc	256..490	CDD:238113	90/251 (36%)
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	90/251 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910