Protein Alignment Rnf149 and H10E21.5

DIOPT Version :9

• Sequence 1: NP_001028307.2
• Gene: Rnf149 / 67702
• MGIID: 2677438
• Length: 394
• Species: Mus musculus
• Sequence 2: NP_497129.1
• Gene: H10E21.5 / 175169
• WormBaseID: WBGene00019185
• Length: 473
• Species: Caenorhabditis elegans
• Alignment Length: 311
• Identity: 94/311 - (30%)
• Similarity: 143/311 - (45%)
• Gaps: 76/311 - (24%)

Mouse    82 PAPAEGCAPDTRFVAPGALGNAPWVALVARGGCTFKDKVLAAARRNASAVVVYNLESNGNATEPM 146
            ||..:.||||.:|                                :.|..|.:......|....:
 Worm    62 PAYTDLCAPDMKF--------------------------------DDSQRVFFCKNCIQNCLSRV 94

Mouse   147 SHAGTGNIVVIMISYPKGREIFDLVQKGIPVKMRIEIG------------------TRHMQEFIS 193
            ..|....::|..:..|..|..:..||  .||....|.|                  |..::.| |
 Worm    95 ETAPKNILIVADVKAPNNRVSWFHVQ--TPVSNIRESGKQCNVENSNAMQSPEETSTDALRSF-S 156

Mouse   194 GQSVVFVAIAFITMMIISLAWLIFYYIQRFLYTGSQFGSQNHRKE---------TKKVIGQLPLH 249
            ..||:||:|:||.:|:||||||:|||:|||.|.        |.|:         .:|.:.::|..
 Worm   157 KTSVLFVSISFIILMVISLAWLVFYYVQRFRYA--------HAKDRLQRRLFNAARKALTRIPTM 213

Mouse   250 TVKHG-EKGIDVDAENCAVCIENFKVKDVIRILPCKHIFHRICIDPWLLDHRTCPMCKLDVIKAL 313
            |:..| .:.:..|   ||||::.::::||||:||||||:|:.|||||||:||||||||.|::|..
 Worm   214 TITPGMTQELQSD---CAVCLDPYQLQDVIRLLPCKHIYHKSCIDPWLLEHRTCPMCKNDILKHF 275

Mouse   314 GYWGDPEDTQELPTPEAAPGRVSVGNLSVTSQDEERSESNL--PSSSSSES 362
            |||.|..:..::||............|.:..|:.:...:::  |.::|..|
 Worm   276 GYWNDIRNDIQMPTNSRGIADDFTIRLELGEQEHQAPSADVISPEANSDTS 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rnf149	NP_001028307.2	PA_GRAIL_like	45..181	CDD:239037	18/98 (18%)
		UPF0233	<193..>220	CDD:299753	17/26 (65%)
		zf-RING_2	263..306	CDD:290367	28/42 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	321..394		7/44 (16%)
H10E21.5	NP_497129.1	HRD1	<150..325	CDD:227568	72/186 (39%)
		RING-H2_GRAIL	226..273	CDD:319582	32/49 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	84	1.000	Domainoid score	I5750
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000832
OrthoInspector	1	1.000	-	-		otm16989
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22765
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X295
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.970