DRSC/TRiP Functional Genomics Resources

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Protein Alignment ST14 and CG4053

DIOPT Version :10

Sequence 1:NP_068813.1 Gene:ST14 / 6768 HGNCID:11344 Length:855 Species:Homo sapiens
Sequence 2:NP_650601.2 Gene:CG4053 / 42070 FlyBaseID:FBgn0038482 Length:265 Species:Drosophila melanogaster


Alignment Length:240 Identity:66/240 - (27%)
Similarity:113/240 - (47%) Gaps:22/240 - (9%)


- Green bases have known domain annotations that are detailed below.


Human   614 RVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTAFLGL 678
            |:|||.:|::|..|:|||:..:.:.|||...:::..|:::|.||.:|   |...|   ....:|.
  Fly    34 RIVGGQEAEDGVAPYQVSIQTIWKTHICSGVILNEQWILTAGHCALD---FSIED---LRIIVGT 92

Human   679 HDQSQRSAPGVQERRLKRIISHPFFN-DFTFDYDIALLELEKPAEYSSMVRPICLPDASHVFPAG 742
            :|   |..|| |.......:.|..:: .:.::.||||:.:.:...::...:.:.|  :....|||
  Fly    93 ND---RLEPG-QTLFPDEALVHCLYDIPYVYNNDIALIHVNESIIFNDRTQIVEL--SREQPPAG 151

Human   743 KAIWVTGWGHTQYGGTGALILQKGEIRVINQTTCENL--LPQQITPRMMCVGFLSGGVDSCQGDS 805
            ..:.:||||..:........||...:.:|....|...  ....|....:|. |...|..:|.|||
  Fly   152 STVTLTGWGAPESSYPTVQYLQTLNLTIIAHEECRERWDFHDGIDIGHICT-FTREGEGACSGDS 215

Human   806 GGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWIK 850
            ||||.   .:|::  .|:|:||..|.. ..|.:|.....::|||:
  Fly   216 GGPLM---WEGKL--VGLVNWGRACGV-GMPDMYANTVYYQDWIR 254

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ST14NP_068813.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..20
SEA 88..>162 CDD:460188
CUB 227..332 CDD:238001
CUB 340..444 CDD:238001
LDLa 454..486 CDD:238060
LDLa 488..523 CDD:238060
LDLa 525..559 CDD:238060
LDLa 567..602 CDD:238060
Tryp_SPc 615..852 CDD:238113 65/239 (27%)
CG4053NP_650601.2 Tryp_SPc 35..256 CDD:238113 65/239 (27%)
Blue background indicates that the domain is not in the aligned region.

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