Protein Alignment ST14 and ndl

DIOPT Version :10

• Sequence 1: NP_068813.1
• Gene: ST14 / 6768
• HGNCID: 11344
• Length: 855
• Species: Homo sapiens
• Sequence 2: NP_523947.2
• Gene: ndl / 38738
• FlyBaseID: FBgn0002926
• Length: 2616
• Species: Drosophila melanogaster
• Alignment Length: 927
• Identity: 219/927 - (23%)
• Similarity: 324/927 - (34%)
• Gaps: 303/927 - (32%)

Human    94 MRITN------ENFVDAYENS------------NSTEFVSLASKVKDALKLLYSGVPFLGPYHKE 140
            :|:.|      |...|.||..            |..|.:.......||..|...| |.:.|.:
  Fly   592 LRVLNANESSSETVTDGYERQLWLKKFEDQARPNQNELIDTFGTALDAKALDKMG-PKINPLN-- 653

Human   141 SAVTAFSEGSVIAYYWSEFSIPQHLVEEAERVMAEERVVMLPPRARSLKSFVVTSVVAFPTDSKT 205
                        .:.|:        ..:|:.:...|||.:   |.|        :.||..:|.:|
  Fly   654 ------------GHTWN--------AADAQILSLCERVAL---RMR--------NKVATMSDGET 687

Human   206 VQR----TQDNSCSFGLHARGVELMRFTTPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLA 266
            .::    |...|..|...|.|         |||.|..        .::..|..:.:..|....:.
  Fly   688 KEKGETFTASPSVQFTSRAPG---------GFPVSGE--------TMKASAQFMFNPNFGMPSIP 735

Human   267 SCDERGSDLVTVYNTLSPMEPHALVQLCGTYPPSYNLTFHSSQNVLLITLITNTERRHPGFEATF 331
            .|     ..:|..|...||..:.     .|:.......|..|.|              ||  |..
  Fly   736 VC-----FYMTPANFRMPMWSNT-----PTFMGMQGAHFGGSSN--------------PG--AGI 774

Human   332 FQLPRM-------------SSCGGRLRKAQGTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFK 383
            |.:|:.             |..||:.........||..|.:....:.|::    ..||
  Fly   775 FFVPQQFGPSGNFFGGSGGSGAGGQGANIFSKNASPQKPTNGQQQVYCSY----MQNQ------- 828

Human   384 FFYLLEPGVPAGTCPKDYVEINGEKYCGERSQFVVTSNSNKITVRFHSDQSYT--DTGFLAEYLS 446
                  .|..||..     :.:.::..|.:|.|   ||:| ..:| |::|:.|  ..|.:. |.|
  Fly   829 ------SGQGAGQS-----QTSSQQQQGGQSAF---SNAN-FKMR-HANQTNTANQQGQII-YAS 876

Human   447 Y----------DSSDPCPGQFTC-RTGRCIRKELRCDGWADCTDHSDELNCSCDAGHQFTCKNKF 500
            |          .|..|.|.||:| ....||.....||...||:|.|||..|        ||.::.
  Fly   877 YAGLPQQPIQERSRCPEPDQFSCFGQQECIPAARWCDNVVDCSDGSDESAC--------TCADRV 933

Human   501 CKPLFWVCDSVNDCGDNSDEQGC-SCPAQTFRC-------------SNGKCLSKSQQCNGKDDCG 551
            .:..  :||...||....||.|| .|.:..:.|             :...|.|:.::|:|..:|.
  Fly   934 DEER--LCDGYEDCPMGEDELGCFGCESLAYSCYENPQDFAKRNRSTISMCYSRLERCDGFMNCL 996

Human   552 DGSDEASCPKVNVVTCTK---------------HTYR------CLNG------LCLSKGNPECDG 589
            :|.||..|..  :||...               |.||      |.||      .|....|...|.
  Fly   997 NGRDEEQCSM--LVTDVADHMSHGASASEGYLYHNYRGDWHPVCNNGEKWAALACQMDENSRMDH 1059

Human   590 KEDCS---------------------------DGSDEKD----------C---DCGLRSFT---- 610
            ....:                           .|.:..|          |   .|||.|.:
  Fly  1060 SASLNVSFQTLTLPGPFIEPSLHAGVHFAQACHGRNSHDSLVDHVAYVKCPPMQCGLPSKSSMLE 1124

Human   611 -----RQA-----------RVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYI 659
                 |:|           |:|||:.....:||:.|:::..|:.| ||.::.|..|::|||||.|
  Fly  1125 HSKRVRRAVSDSKEIVGDGRIVGGSYTSALQWPFVVAIYRNGKFH-CGGTIYSDRWIISAAHCVI 1188

Human   660 DDRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYS 724
            :...:.|.      ...||..:|..| |..|.:.:..::.|..:...:...|::||.|..|.:::
  Fly  1189 NYGKYFYE------VRAGLLRRSSYS-PATQIQPVSHVVVHQAYERRSMRNDLSLLRLLNPLQFN 1246

Human   725 SMVRPICLPDASHVFPAGKAIW---------VTGWGHTQYGGTGALILQKG-------EIRVINQ 773
            ..|:||||||..........||         |.|||         .|.:||       ::.|..:
  Fly  1247 RWVKPICLPDKGRTTVGDDWIWGPVEHTLCTVVGWG---------AIREKGPSSDPMRQVIVPIR 1302

Human   774 TTCENLLPQQITPRMMCVGFLSGGVDSCQGDSGGPL--SSVEADGRIFQAGVVSWGDGCAQRNKP 836
            ..|.:  |:......:|.|...||.|:|||||||||  .||......:.|||||.|:|||:..:.
  Fly  1303 KKCTD--PEDQASEDICAGDPDGGRDACQGDSGGPLFCRSVSNPDEFYLAGVVSHGNGCARPQEF 1365

Human   837 GVYTRLPLFRDWIKENT 853
            |||||:.|:.||::..|
  Fly  1366 GVYTRVTLYLDWLEMAT 1382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ST14	NP_068813.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		SEA	88..>162	CDD:460188	15/85 (18%)
		CUB	227..332	CDD:238001	18/104 (17%)
		CUB	340..444	CDD:238001	22/105 (21%)
		LDLa	454..486	CDD:238060	14/32 (44%)
		LDLa	488..523	CDD:238060	8/34 (24%)
		LDLa	525..559	CDD:238060	10/46 (22%)
		LDLa	567..602	CDD:238060	11/98 (11%)
		Tryp_SPc	615..852	CDD:238113	83/254 (33%)
ndl	NP_523947.2	LDLa	891..927	CDD:238060	15/35 (43%)
		Tryp_SPc	1145..1379	CDD:238113	83/252 (33%)
		LDLa	1399..1430	CDD:238060
		LDLa	1710..1743	CDD:238060
		LDLa	1776..1811	CDD:238060
		DUF1986	2041..2158	CDD:286432
		LDLa	2309..2339	CDD:197566
		LDLa	2350..2383	CDD:197566
		LDLa	2421..2457	CDD:238060