Protein Alignment ST14 and CG8170

DIOPT Version :10

• Sequence 1: NP_068813.1
• Gene: ST14 / 6768
• HGNCID: 11344
• Length: 855
• Species: Homo sapiens
• Sequence 2: NP_610441.2
• Gene: CG8170 / 35908
• FlyBaseID: FBgn0033365
• Length: 855
• Species: Drosophila melanogaster
• Alignment Length: 942
• Identity: 221/942 - (23%)
• Similarity: 322/942 - (34%)
• Gaps: 278/942 - (29%)

Human    97 TNENFVDAYENSNSTEFVSLASKVKDALKL---------------------LYSGVPFLGPYHKE 140
            |:||..:....|.||......|::..|:.|                     |.||...| |:...
  Fly     5 TDENNTNTTTASRSTRNTWRWSRLALAVSLFAYCCCASSAATPTTSVTTAALLSGHQLL-PWQTA 68

Human   141 SAVTAFSEGSVIAYYWSEFSIPQHLVEEAERVMAEERVVMLPPRARSLKSFVVTSVVAFPTD--- 202
            :|..|.:..:....|....|..:|           :.:.....|.|| ...||.|..::.|.
  Fly    69 AATAATTPSTARNLYAPHQSFSRH-----------DDISFKDLRQRS-DGTVVQSFGSYRTARQF 121

Human   203 ---SKTVQRTQDNSCSFGLHARGVEL--------MRFTTPGFPDSPYPAHARCQW---------- 246
               |.|.||..|.:... :.|..|||        .:...|..|::......|..:
  Fly   122 GGYSTTAQRRSDPAVEI-IPAPSVELPQGELITVPKQLVPTMPENVTRQGRRRNYMYIPLQTEGE 185

Human   247 -------ALRGDADSVLSLTFRSFD--LASCDERGSDLVTVYNTLSPMEPHALVQLCGTYPPSYN 302
                   .||...::.||......|  .|...|.|:||.|  ....|.:|...::|........:
  Fly   186 NGSAALLQLRPSRNATLSALGPPADGVAAVAHEFGADLAT--QGSGPEQPPLALELGPERTERSD 248

Human   303 L-TFHSSQNVLLITLITNTERRHPGFEATFFQLPRMSSCGGRLRKAQGTFNSPYYP--------- 357
            | ...||.:.|......||.||      ..||.|..|     |:.|     ||::|
  Fly   249 LMAAASSTDKLEYAEPENTSRR------VGFQFPSYS-----LKPA-----SPFHPQAYREDNPI 297

Human   358 ------GHYPPN--------IDCTWNIEVPNNQHVK----------VRFKFFYLLEPGVPAGTCP 398
                  |.|.|.        :......|....:|.:          ..|:|     ||:.:.:.|
  Fly   298 FGDTSAGGYEPQPYSEDASPVPPPTQYEQHETRHTRQLYFDSDTASSSFEF-----PGLVSNSKP 357

Human   399 ------KDYV----EINGEKYCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLSYDSSDPC 453
                  :|.|    :|||                 .||.   ..|.....||......:.:..|.
  Fly   358 HGLKLYRDDVTKFGDING-----------------PITA---LPQQRPQRGFYFGDTEFRTGPPA 402

Human   454 PGQFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDAGHQFTCKNKFC--------KPLFWVCDS 510
            |          :|:......:.:....|:         :|.|.|:::.        :.:|...|:
  Fly   403 P----------VRQFGPQKNFQEYVGPSE---------YQGTRKSRYYPYKSSRSPRVVFPTNDN 448

Human   511 VNDCGDNSDEQGCSCPA--------------QTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCP- 560
            |...|. |...|.|.|:              |.|..:....:...:......|....|:..|.|
  Fly   449 VGTTGP-SGPAGSSGPSGNGVYFSDNIAFRDQNFGINELAAVQDVRNDYSLQDLDSASEATSSPQ 512

Human   561 -------KVNVVTCTKHTYRCLNGLC-------LSKG--NPECDG-------------------- 589
                   ||::.|.|:..:|  .|.|       ||.|  ...|||
  Fly   513 SASTFKEKVDITTDTECQHR--GGTCEFFLGCWLSGGLIQGTCDGLLRGCCHRTAKSANLGSSDF 575

Human   590 -----------KEDCSDGSDEKDCDCGLRSFTRQARVVGGTDADEGEWPWQVSLHALGQGHICGA 643
                       :::....::|..|...|...|.|.|:|||.||..|.:|||..:. :|... ||.
  Fly   576 VGNAVDLTDLPQKNYGPVNNEPSCGISLAKQTAQRRIVGGDDAGFGSFPWQAYIR-IGSSR-CGG 638

Human   644 SLISPNWLVSAAHCYIDDRGFRYSDPTQWTAFLGLHDQSQRSAP------GVQERRLKRIISHPF 702
            ||||...:|:|.||      ...:.|.|....||.:..:....|      ||     :||..||:
  Fly   639 SLISRRHVVTAGHC------VARATPRQVHVTLGDYVINSAVEPLPAYTFGV-----RRIDVHPY 692

Human   703 FNDFTFD---YDIALLELEKPAEYSSMVRPICLPDASHVFPAGKAIWVTGWGHTQYGG-TGALIL 763
            |. ||..   :||::|.||:...:...:.|||||:.:..| .||..|..|||....|. .....|
  Fly   693 FK-FTPQADRFDISVLTLERTVHFMPHIAPICLPEKNEDF-LGKFGWAAGWGALNPGSRLRPKTL 755

Human   764 QKGEIRVINQTTCE-----NLLPQQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGV 823
            |..::.||....||     |.:...|...|:|.|:.:||.|||||||||||.. :.:||.:..||
  Fly   756 QAVDVPVIENRICERWHRQNGINVVIYQEMLCAGYRNGGKDSCQGDSGGPLMH-DKNGRWYLIGV 819

Human   824 VSWGDGCAQRNKPGVYTRLPLFRDWIKENTGV 855
            ||.|..||.|.:||:|..:....||:....|:
  Fly   820 VSAGYSCASRGQPGIYHSVSKTVDWVSYVVGL 851

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ST14	NP_068813.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		SEA	88..>162	CDD:460188	18/85 (21%)
		CUB	227..332	CDD:238001	25/124 (20%)
		CUB	340..444	CDD:238001	25/146 (17%)
		LDLa	454..486	CDD:238060	3/31 (10%)
		LDLa	488..523	CDD:238060	8/42 (19%)
		LDLa	525..559	CDD:238060	5/47 (11%)
		LDLa	567..602	CDD:238060	11/74 (15%)
		Tryp_SPc	615..852	CDD:238113	91/251 (36%)
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	91/249 (37%)