Protein Alignment SSTR4 and AstC-R1

DIOPT Version :10

• Sequence 1: NP_001043.2
• Gene: SSTR4 / 6754
• HGNCID: 11333
• Length: 388
• Species: Homo sapiens
• Sequence 2: NP_649040.2
• Gene: AstC-R1 / 40020
• FlyBaseID: FBgn0036790
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 386
• Identity: 132/386 - (34%)
• Similarity: 211/386 - (54%)
• Gaps: 41/386 - (10%)

Human     1 MSAPSTLPPGGEEGL-GTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVG 64
            :|..||:.|  ||.| ||..|:          .:..:|....  .|.:..: .:|..||::||.|
  Fly    45 ISGSSTIQP--EESLYGTDLPT----------YQHCIATRNS--FADLFTV-VLYGFVCIIGLFG 94

Human    65 NALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLN 129
            |.|||:|:||::||:|.||||:||||||||.|::.:||:..:..:..|.||..:|:|.:....:.
  Fly    95 NTLVIYVVLRFSKMQTVTNIYILNLAVADECFLIGIPFLLYTMRICSWRFGEFMCKAYMVSTSIT 159

Human   130 MFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQ 194
            .|||...|.::|.|||:||.||:.:..||...:||:::...|..|.::.||:.::|.|.....|.
  Fly   160 SFTSSIFLLIMSADRYIAVCHPISSPRYRTLHIAKVVSAIAWSTSAVLMLPVILYASTVEQEDGI 224

Human   195 AVACNLQWP-----HPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGW--QQRRR 252
            ..:||:.||     |.  ...|::|||.|||..|:..|...|.|::.|:|:|..:.|.  :::||
  Fly   225 NYSCNIMWPDAYKKHS--GTTFILYTFFLGFATPLCFILSFYYLVIRKLRSVGPKPGTKSKEKRR 287

Human   253 SEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLI-------LSYANSCANPIL 310
            :.:|:|||||.|:.|::|||:|.::.|:..:........::.:.::       |.|:||..||||
  Fly   288 AHRKVTRLVLTVISVYILCWLPHWISQVALIHSNPAQRDLSRLEILIFLLLGALVYSNSAVNPIL 352

Human   311 YGFLSDNFRR-FFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGG------AGCMCPPL 364
            |.|||:|||: ||:...|:....:...  .:.||..:.....|.:||      :....|||
  Fly   353 YAFLSENFRKSFFKAFTCMNKQDINAQ--LQLEPSVFTKQGSKKRGGSKRLLTSNPQIPPL 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SSTR4	NP_001043.2	7tmA_SSTR4	48..322	CDD:320639	109/288 (38%)
		TM helix 1	49..75	CDD:320639	12/25 (48%)
		TM helix 2	82..108	CDD:320639	15/25 (60%)
		TM helix 3	119..149	CDD:320639	11/29 (38%)
		TM helix 4	161..183	CDD:320639	6/21 (29%)
		TM helix 5	208..237	CDD:320639	11/28 (39%)
		TM helix 6	252..282	CDD:320639	14/29 (48%)
		TM helix 7	290..315	CDD:320639	10/31 (32%)
AstC-R1	NP_649040.2	7tmA_AstC_insect	78..364	CDD:320222	109/288 (38%)
		TM helix 1	79..105	CDD:320222	12/26 (46%)
		TM helix 2	112..138	CDD:320222	15/25 (60%)
		TM helix 3	149..179	CDD:320222	11/29 (38%)
		TM helix 4	191..213	CDD:320222	6/21 (29%)
		TM helix 5	241..270	CDD:320222	11/28 (39%)
		TM helix 6	287..317	CDD:320222	14/29 (48%)
		TM helix 7	332..357	CDD:320222	10/24 (42%)