DRSC/TRiP Functional Genomics Resources

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Protein Alignment SSTR1 and AstC-R1

DIOPT Version :9

Sequence 1:NP_001040.1 Gene:SSTR1 / 6751 HGNCID:11330 Length:391 Species:Homo sapiens
Sequence 2:NP_649040.2 Gene:AstC-R1 / 40020 FlyBaseID:FBgn0036790 Length:483 Species:Drosophila melanogaster


Alignment Length:351 Identity:127/351 - (36%)
Similarity:206/351 - (58%) Gaps:27/351 - (7%)


- Green bases have known domain annotations that are detailed below.


Human    64 IYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGAL 128
            :|..||::||.||::||||:||::||:|.|||||||||:|||..::.:|||:.:..:..|.||..
  Fly    83 LYGFVCIIGLFGNTLVIYVVLRFSKMQTVTNIYILNLAVADECFLIGIPFLLYTMRICSWRFGEF 147

Human   129 LCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIV 193
            :|:..:...::..|||...|.::|.|||:||.|||.:.|||...:||||:...|..|.:::||::
  Fly   148 MCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTLHIAKVVSAIAWSTSAVLMLPVI 212

Human   194 VFSRTAANSDG-TVACNMLMPEPAQRWL-VGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALK 256
            :::.|....|| ..:||::.|:..::.. ..|:||||.:||..|:..|...|.|:|.|:|.|..|
  Fly   213 LYASTVEQEDGINYSCNIMWPDAYKKHSGTTFILYTFFLGFATPLCFILSFYYLVIRKLRSVGPK 277

Human   257 AGW--QQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVI-------LG 312
            .|.  ::::|:.||:|.:|:.|:.|:::||:|.::.|:..:.:......:|:|.::       |.
  Fly   278 PGTKSKEKRRAHRKVTRLVLTVISVYILCWLPHWISQVALIHSNPAQRDLSRLEILIFLLLGALV 342

Human   313 YANSCANPILYGFLSDNFKRS-FQRILCLSWMDNAAE---EPVDYYATALKSRAYS--------- 364
            |:||..|||||.|||:||::| |:...|::..|..|:   ||..:.....|.|..|         
  Fly   343 YSNSAVNPILYAFLSENFRKSFFKAFTCMNKQDINAQLQLEPSVFTKQGSKKRGGSKRLLTSNPQ 407

Human   365 VEDFQPENLESGGVFRNGTCTSRITT 390
            :....|.|   .|...:.|.||..||
  Fly   408 IPPLLPLN---AGNNNSSTTTSSTTT 430

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SSTR1NP_001040.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..50
7tmA_SSTR1 59..334 CDD:320636 110/281 (39%)
TM helix 1 61..85 CDD:320636 11/20 (55%)
TM helix 2 94..115 CDD:320636 13/20 (65%)
TM helix 3 131..153 CDD:320636 4/21 (19%)
TM helix 4 176..192 CDD:320636 5/15 (33%)
TM helix 5 221..244 CDD:320636 9/22 (41%)
TM helix 6 270..292 CDD:320636 7/21 (33%)
TM helix 7 302..327 CDD:320636 12/31 (39%)
AstC-R1NP_649040.2 7tm_4 88..368 CDD:304433 109/279 (39%)
7tm_1 94..353 CDD:278431 97/258 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 223 1.000 Domainoid score I2578
eggNOG 1 0.900 - - E33208_3BCR0
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 243 1.000 Inparanoid score I3312
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000463
OrthoInspector 1 1.000 - - mtm8609
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24229
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3938
SonicParanoid 1 1.000 - - X22
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
109.990

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