Protein Alignment SRMS and PIN3

DIOPT Version :9

• Sequence 1: NP_543013.1
• Gene: SRMS / 6725
• HGNCID: 11298
• Length: 488
• Species: Homo sapiens
• Sequence 2: NP_015480.1
• Gene: PIN3 / 856277
• SGDID: S000006358
• Length: 215
• Species: Saccharomyces cerevisiae
• Alignment Length: 272
• Identity: 60/272 - (22%)
• Similarity: 87/272 - (31%)
• Gaps: 100/272 - (36%)

Human     5 LRRRLAFL-------SFFWDKI-------WPAGGEPDHGTPGSLDPNTDPVPTLPAEPCSPFPQL 55
            :|..|.||       :..:|:|       |.....|.:.:|.||                   :.
Yeast    13 IRTELDFLKGSNVISNDVYDQINKSLPAKWDPANAPRNASPASL-------------------EY 58

Human    56 FLALYDFTARCGGELSVRRGDRLCALEEGGGYIFARRLSGQPSAGLVPITHVAKA-----SPETL 115
            ..|||.|..:..|:|.::.||::..||:.....:....:|:  .|:.|..:|..|     .|..|
Yeast    59 VEALYQFDPQQDGDLGLKPGDKVQLLEKLSPEWYKGSCNGR--TGIFPANYVKPAFSGSNGPSNL 121

Human   116 SDQPWYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQAKVCHYRVSMAADGSLY 180
            ...|.|       :||:|...|.....|                                  |.|
Yeast   122 PPPPQY-------KAQELQQIPTQNSAA----------------------------------SSY 145

Human   181 LQKGRLFPGLEELLTYYKANWKLIQNPLLQPCM---PQKAPRQDVWERPHSEF-ALGRKLGE-GY 240
            .|:.  ||  .....||       |.|..||..   ||:..:|...:..||.. :.|.|||. ..
Yeast   146 QQQP--FP--PPSTNYY-------QQPQQQPQQAPPPQQQQQQQQHQSSHSHLKSFGSKLGNAAI 199

Human   241 FGEVWEGLWLGS 252
            ||   .|..:||
Yeast   200 FG---AGASIGS 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRMS	NP_543013.1	SH3_Srms	55..109	CDD:212780	14/53 (26%)
		SH2	119..197	CDD:301589	12/77 (16%)
		PTKc_Srm_Brk	223..483	CDD:133248	11/32 (34%)
		STYKc	232..480	CDD:214568	9/22 (41%)
PIN3	NP_015480.1	SH3	58..110	CDD:418401	14/53 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000