Protein Alignment SRD5A2 and TSC13

DIOPT Version :9

• Sequence 1: NP_000339.2
• Gene: SRD5A2 / 6716
• HGNCID: 11285
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_010269.1
• Gene: TSC13 / 851547
• SGDID: S000002173
• Length: 310
• Species: Saccharomyces cerevisiae
• Alignment Length: 181
• Identity: 43/181 - (23%)
• Similarity: 68/181 - (37%)
• Gaps: 37/181 - (20%)

Human    83 LLGLF--CLHYFHRTFVYSLLNRGRPYPAILILRGTAFCTGNGVLQGYYLIYCAEYPDGWYTDIR 145
            :..||  |.||:   .:..|::.|        ..|..|..||..|..||.....:       |:.
Yeast   158 IFNLFKNCFHYW---VLSGLISFG--------YFGYGFPFGNAKLFKYYSYLKLD-------DLS 204

Human   146 FSLGVFL------FILGMGINIHSDYILRQLRKPGEISYRIP-QGGLFTYVSGANFLGEIIEWIG 203
            ..:|:|:      |...:.:.:..||    .:|.|....|:| ..|:|......|:..|:..||
Yeast   205 TLIGLFVLSELWNFYCHIKLRLWGDY----QKKHGNAKIRVPLNQGIFNLFVAPNYTFEVWSWI- 264

Human   204 YALATWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFEDYPKSRKALIPFIF 254
                 |......|..|::.||.:.....:.:..|..:.|...|..||||:|
Yeast   265 -----WFTFVFKFNLFAVLFLTVSTAQMYAWAQKKNKKYHTRRAFLIPFVF 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRD5A2	NP_000339.2	Steroid_dh	105..254	CDD:251363	35/155 (23%)
TSC13	NP_010269.1	PLN02560	1..297	CDD:178174	36/166 (22%)
		Steroid_dh	154..310	CDD:251363	42/179 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C159047282
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840