DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment SRC and SLA1

DIOPT Version :10

Sequence 1:XP_047296363.1 Gene:SRC / 6714 HGNCID:11283 Length:562 Species:Homo sapiens
Sequence 2:NP_009546.1 Gene:SLA1 / 852276 SGDID:S000000103 Length:1244 Species:Saccharomyces cerevisiae


Alignment Length:382 Identity:74/382 - (19%)
Similarity:116/382 - (30%) Gaps:168/382 - (43%)


- Green bases have known domain annotations that are detailed below.


Human   117 ALYDYE--SRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYF 179
            |:||||  ...:.:|:|.:.:...:.::.:.||.|..|..:.:.|:||.|||.|.:...:::   
Yeast    76 AIYDYEQVQNADEELTFHENDVFDVFDDKDADWLLVKSTVSNEFGFIPGNYVEPENGSTSKQ--- 137

Human   180 GKITRRESERLLLNAENPRGT--------------FL---------------------------- 202
                    |:....||.|..|              ||                            
Yeast   138 --------EQAPAAAEAPAATPAAAPASAAVLPTNFLPPPQHNDRARMMQSKEDQAPDEDEEGPP 194

Human   203 -------VRESETTKGAYC-------LSVSDFD----------NAKGLNVKHY------------ 231
                   ...:|||.....       ||.||.|          |:...||.::            
Yeast   195 PAMPARPTATTETTDATAAAVRSRTRLSYSDNDNDDEEDDYYYNSNSNNVGNHEYNTEYHSWNVT 259

Human   232 -------KIRKLDSGGFYITSRTQFN-----SLQQLVAY--YSKH-----ADGLCHRLTTVCPTS 277
                   |..||..|...|....|..     |:.:||:|  ..||     .|             
Yeast   260 EIEGRKKKKAKLSIGNNKINFIPQKGTPHEWSIDKLVSYDNEKKHMFLEFVD------------- 311

Human   278 KPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVW--MGTWNGTTRVAIKTLKPGTMSPEAFLQEA 340
                          |..||.|.......| .|:.  :|.:.|.:|      .||       |:|.
Yeast   312 --------------PYRSLELHTGNTTTC-EEIMNIIGEYKGASR------DPG-------LREV 348

Human   341 QVMKKLRHEKLVQL---------YAVVSEEPIYIVTEYMSKG----SLLDFLKGETG 384
            ::..|.:...:||.         ..:.|.:.:||:.:..||.    .|:|  .|::|
Yeast   349 EMASKSKKRGIVQYDFMAESQDELTIKSGDKVYILDDKKSKDWWMCQLVD--SGKSG 403

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SRCXP_047296363.1 SH3_Src 114..169 CDD:212941 17/53 (32%)
SH2_Src_Src 173..273 CDD:198228 31/196 (16%)
PTKc_Src 286..562 CDD:270656 25/114 (22%)
SLA1NP_009546.1 SH3_Sla1p_1 7..64 CDD:212707
SH3 73..127 CDD:473055 15/50 (30%)
SH3_Sla1p_3 356..412 CDD:212709 11/50 (22%)
SHD1 489..554 CDD:427630
SAM_SLA1_fungal 655..716 CDD:188931
DUF5585 <723..1040 CDD:465521
Med15 967..>1230 CDD:312941
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.