DRSC/TRiP Functional Genomics Resources

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Protein Alignment SPTBN1 and Dys

DIOPT Version :9

Sequence 1:NP_003119.2 Gene:SPTBN1 / 6711 HGNCID:11275 Length:2364 Species:Homo sapiens
Sequence 2:NP_001036722.1 Gene:Dys / 42327 FlyBaseID:FBgn0260003 Length:3598 Species:Drosophila melanogaster


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SPTBN1NP_003119.2 Actin-binding 2..275
CH_SPTBN1_rpt1 3..156 CDD:409165
SAC6 48..>530 CDD:227401
CH_SPTB_like_rpt2 173..277 CDD:409097
Spectrin 1. /evidence=ECO:0000255 303..411
Spectrin 2. /evidence=ECO:0000255 423..525
SPEC 530..743 CDD:238103
Spectrin 3. /evidence=ECO:0000255 530..636
Spectrin 4. /evidence=ECO:0000255 639..742
SPEC 642..849 CDD:238103
Spectrin 5. /evidence=ECO:0000255 745..847
Spectrin 6. /evidence=ECO:0000255 850..952
SPEC 851..1061 CDD:238103
Spectrin 7. /evidence=ECO:0000255 957..1060
SPEC 958..1169 CDD:238103
Spectrin 8. /evidence=ECO:0000255 1063..1166
Spectrin 9. /evidence=ECO:0000255 1170..1258
SPEC 1171..1380 CDD:238103
Spectrin 10. /evidence=ECO:0000255 1276..1376
SPEC 1381..1592 CDD:238103
Spectrin 11. /evidence=ECO:0000255 1381..1482
Spectrin 12. /evidence=ECO:0000255 1486..1590
Interaction with ANK2. /evidence=ECO:0000269|PubMed:15262991 1563..2093
SPEC 1593..1805 CDD:238103
SPEC 1806..2027 CDD:238103
Spectrin 2017..>2075 CDD:395348
Spectrin 17. /evidence=ECO:0000255 2018..2097
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2089..2196
Mediates interaction with CAMSAP1. /evidence=ECO:0000269|PubMed:24117850 2149..2177
PH_beta_spectrin 2200..2305 CDD:269975
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2309..2364
DysNP_001036722.1 CH 13..111 CDD:278723
CH 129..225 CDD:278723
SPEC 312..525 CDD:238103
SbcC <325..957 CDD:223496
Smc <816..1591 CDD:224117
SPEC 1174..1365 CDD:238103
SPEC 1289..1485 CDD:295325
SPEC 2369..2576 CDD:238103
SPEC 2477..2714 CDD:238103
WW 2852..2882 CDD:238122
EF-hand_2 2883..2997 CDD:286194
EF-hand_3 3001..3100 CDD:286195
ZZ_dystrophin 3110..3158 CDD:239074
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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