DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rnf128 and SPAC57A7.09

DIOPT Version :9

Sequence 1:	NP_075759.3	Gene:	Rnf128 / 66889	MGIID:	1914139	Length:	428	Species:	Mus musculus
Sequence 2:	NP_593372.1	Gene:	SPAC57A7.09 / 2542187	PomBaseID:	SPAC57A7.09	Length:	372	Species:	Schizosaccharomyces pombe

Alignment Length:	354	Identity:	74/354 - (20%)
Similarity:	137/354 - (38%)	Gaps:	101/354 - (28%)

- Green bases have known domain annotations that are detailed below.

Mouse    43 WTAYLNVSWRVPHTGVNRTVWELSEEGVYGQ---DSPLEPVSGVLVPPDGPGALNACNPHTNFTV 104
            :.|..:|:.::|...|  |:|  |.:.|:|:   ::....|..:.:|.:....::.| |:.|.|.
pombe    39 FAASTDVAIQLPDRNV--TLW--SRQAVFGKHFTNASATTVINLYLPSNFQEDMSGC-PNRNDTD 98

Mouse   105 PTVW----------------------GSTVQ-----------VSWLALIQRGGGCTFADKIHLAS 136
            .:.:                      .:.||           :....|:|| |.||:.||...|.
pombe    99 ASYFYENDIIDYDIEYIEQKSYSSKPSARVQKDDGGESKDEAILDFLLVQR-GKCTYFDKALEAQ 162

Mouse   137 ERGASGAVI-FNFPGTRNEVIPMSHPGAGD-----IVAIMIG----NLKGTKILQSIQRGIQV-T 190
            ..|..|.:: .|...:...:..|..|...|     |.::.:.    ||..:.:|.|.::.::: .
pombe   163 RLGFKGVIVGDNRSPSSFRLHYMVAPDKVDESKVHIPSLFVSTSSYNLLWSDLLHSYRQPLKLYA 227

Mouse   191 MVIEVGKKHGPWVNHYS---IFFVSVSFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAK 252
            ...|:|....|::..:|   |..::|.     |..:..||       |..|.:|:.:|
pombe   228 KPEELGDMFWPFLLCFSPSIIMLITVQ-----ALAIRKFI-------RTYRTKSKTRR------- 273

Mouse   253 KAIGKLQLRTL-KQG----DKEI-------------------GPDGDSCAVCIELYKPNDLVRIL 293
             .|..|..||: ::|    ::||                   ...|..|.:|:|.:...|.|..|
pombe   274 -FIEDLPSRTISREGFYSEEEEIENSTQNGELVPLMDESTRRATFGVECVICLESFTKGDKVVAL 337

Mouse   294 TCNHIFHKTCVDPWLLEHR-TCPMCKCDI 321
            .|.|.||:.|:..|::::| .||.|..::
pombe   338 PCKHEFHRPCIAKWIVDYRHACPTCNTEV 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rnf128	NP_075759.3	PA_GRAIL_like	48..193	CDD:239037	36/191 (19%)
		zf-RING_2	275..318	CDD:290367	15/43 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	342..428
SPAC57A7.09	NP_593372.1	COG5540	1..369	CDD:227827	74/354 (21%)
		Peptidases_S8_S53	<144..211	CDD:299169	17/67 (25%)
		zf-RING_2	320..362	CDD:290367	15/41 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4628
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810