Protein Alignment SPARC and sparc

DIOPT Version :10

• Sequence 1: NP_001296373.1
• Gene: SPARC / 6678
• HGNCID: 11219
• Length: 341
• Species: Homo sapiens
• Sequence 2: NP_989347.1
• Gene: sparc / 394973
• XenbaseID: XB-GENE-1009630
• Length: 300
• Species: Xenopus tropicalis
• Alignment Length: 295
• Identity: 242/295 - (82%)
• Similarity: 269/295 - (91%)
• Gaps: 3/295 - (1%)

Human     1 MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEVSVGANPVQVEVGEFDDGAEETEEE 65
            ||.|:||:|||.|:|||||||:|||:|.||:|:.   .||.:|||||||||||||||...|.|||
 Frog     1 MRVWVFFVLCLVGKALAAPQQDALPEEEEVIEDV---PTEETVGANPVQVEVGEFDDAVNEEEEE 62

Human    66 VVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKC 130
            ..:||||.|||||||||||:||:||||||||||::||:.:.||||||..||||::||||||||||
 Frog    63 EPSENPCLNHHCKHGKVCEVDESNTPMCVCQDPSTCPSSLAEFEKVCGTDNKTYESSCHFFATKC 127

Human   131 TLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLR 195
            ||||||||||||||||||||||.||||:||:|||||||||||||||:||||||:||||.||||||
 Frog   128 TLEGTKKGHKLHLDYIGPCKYIAPCLDNELSEFPLRMRDWLKNVLVSLYERDENNNLLNEKQKLR 192

Human   196 VKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLI 260
            ||||||||||||||||.:|||||||||||||||||||||||||||||||||||||||:|||||||
 Frog   193 VKKIHENEKRLEAGDHSMELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELSPLRAPLI 257

Human   261 PMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKQR 295
            ||||||||||:.||.||||||||:|||.|||||::
 Frog   258 PMEHCTTRFFDECDTDNDKYIALEEWAKCFGIKEQ 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPARC	NP_001296373.1	FSL_SPARC	71..152	CDD:238649	67/80 (84%)
		EFh_SPARC_like	155..294	CDD:320010	125/138 (91%)
		EF-hand motif	227..260	CDD:320010	31/32 (97%)
		EF-hand motif	262..294	CDD:320010	26/31 (84%)
sparc	NP_989347.1	FSL_SPARC	68..149	CDD:238649	67/80 (84%)
		EFh_SPARC_SPARC	152..291	CDD:320014	125/138 (91%)
		EF-hand motif	224..257	CDD:320014	31/32 (97%)
		EF-hand motif	259..291	CDD:320014	26/31 (84%)