Protein Alignment SPARC and magu

DIOPT Version :10

• Sequence 1: NP_001296373.1
• Gene: SPARC / 6678
• HGNCID: 11219
• Length: 341
• Species: Homo sapiens
• Sequence 2: NP_610548.2
• Gene: magu / 36048
• FlyBaseID: FBgn0262169
• Length: 613
• Species: Drosophila melanogaster
• Alignment Length: 261
• Identity: 56/261 - (21%)
• Similarity: 87/261 - (33%)
• Gaps: 82/261 - (31%)

Human   100 SCPAPIGEFE----KVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSEL 160
            :|.|..||.:    .||..|.:|:.:.||....:|      .||::.|.|.|.|.   .||  |.
  Fly    30 ACAAKQGECDDNEGPVCGTDGQTYPTRCHLLRAQC------GGHQVSLKYSGSCN---ACL--EA 83

Human   161 TEFPLRMRDWLKNVLVTLYERD-------------------------EDNNLLTEKQKLRVKKIH 200
            .:|..|.::......|....:|                         :||.....|.|||.:...
  Fly    84 VKFARRQQERDPGYFVPRCRKDGNFAAMQCYGNNGCWCSDSQGRPIADDNKQFRRKGKLRCRANR 148

Human   201 ENEKRL------------------EAGDHPVELLARDFEKNYN---MYIFP-------------- 230
            .:.:||                  |||.......::.....:|   |.:|.
  Fly   149 RDRRRLASHQIGYNPDTSASKGSSEAGSTAHRTCSKSDRSQFNTNLMRMFRNEAQSFFRQPSLSD 213

Human   231 ---VHWQFGQLDQHPIDGYLSHTELAPLRAPL---IPMEHCTTRFFETCDLDNDKYIALDEWAGC 289
               :.|||.:||.:. :..|...|:..|:..|   :....|...|.:.||:..|..:...||:.|
  Fly   214 SHILEWQFSKLDTNG-NKLLDRQEIRELKKVLRRNVKPRRCGRTFGKYCDVTKDANLNWLEWSVC 277

Human   290 F 290
            |
  Fly   278 F 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPARC	NP_001296373.1	FSL_SPARC	71..152	CDD:238649	17/55 (31%)
		EFh_SPARC_like	155..294	CDD:320010	39/202 (19%)
		EF-hand motif	227..260	CDD:320010	10/52 (19%)
		EF-hand motif	262..294	CDD:320010	9/29 (31%)
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052	12/44 (27%)
		TY	88..139	CDD:238114	5/50 (10%)
		EFh_SPARC_SMOC	182..280	CDD:320013	21/98 (21%)
		EF-hand motif	213..245	CDD:320013	8/32 (25%)
		EF-hand motif	250..280	CDD:320013	9/29 (31%)
		TY	396..463	CDD:238114
		EFh_SPARC_SMOC	475..577	CDD:320013
		EF-hand motif	512..544	CDD:320013
		EF-hand motif	549..577	CDD:320013