Protein Alignment SPARC and sparc

DIOPT Version :10

• Sequence 1: NP_001296373.1
• Gene: SPARC / 6678
• HGNCID: 11219
• Length: 341
• Species: Homo sapiens
• Sequence 2: NP_001001942.1
• Gene: sparc / 321357
• ZFINID: ZDB-GENE-030131-9
• Length: 291
• Species: Danio rerio
• Alignment Length: 295
• Identity: 228/295 - (77%)
• Similarity: 254/295 - (86%)
• Gaps: 12/295 - (4%)

Human     1 MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEVSVGANPVQVEVGEFDDGAEETEEE 65
            ||.|||||.||||:.||||.:|         |..|.|  |:.||.||||||.||||: |.|..|:
Zfish     1 MRVWIFFLFCLAGKTLAAPTEE---------EPAVEE--ELEVGINPVQVETGEFDE-AIEVVED 53

Human    66 VVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKC 130
            |:|||||.|||||.|||||:|::|.||||||||.:||||||:||.||..:|||::||||||||||
Zfish    54 VIAENPCLNHHCKKGKVCEVDDSNQPMCVCQDPLTCPAPIGDFEHVCGTNNKTYESSCHFFATKC 118

Human   131 TLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLR 195
            :|||||||||||:|||||||||.|||::||.||||||||||||||||||||||||||||||||||
Zfish   119 SLEGTKKGHKLHIDYIGPCKYIAPCLENELNEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLR 183

Human   196 VKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLI 260
            ||||:||||||:||||.::|||.|||||||||||||||||||||||||||:||||||||||||||
Zfish   184 VKKIYENEKRLQAGDHSLDLLALDFEKNYNMYIFPVHWQFGQLDQHPIDGFLSHTELAPLRAPLI 248

Human   261 PMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKQR 295
            |||||||.|||.||.|.||||||:|||.|||||::
Zfish   249 PMEHCTTSFFEQCDADQDKYIALEEWANCFGIKEQ 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPARC	NP_001296373.1	FSL_SPARC	71..152	CDD:238649	63/80 (79%)
		EFh_SPARC_like	155..294	CDD:320010	122/138 (88%)
		EF-hand motif	227..260	CDD:320010	31/32 (97%)
		EF-hand motif	262..294	CDD:320010	25/31 (81%)
sparc	NP_001001942.1	FSL_SPARC	59..140	CDD:238649	63/80 (79%)
		EFh_SPARC_SPARC	143..282	CDD:320014	122/138 (88%)
		EF-hand motif	215..248	CDD:320014	31/32 (97%)
		EF-hand motif	250..282	CDD:320014	25/31 (81%)