Protein Alignment SPARC and ost-1

DIOPT Version :10

• Sequence 1: NP_001296373.1
• Gene: SPARC / 6678
• HGNCID: 11219
• Length: 341
• Species: Homo sapiens
• Sequence 2: NP_500039.1
• Gene: ost-1 / 176931
• WormBaseID: WBGene00003893
• Length: 264
• Species: Caenorhabditis elegans
• Alignment Length: 304
• Identity: 95/304 - (31%)
• Similarity: 148/304 - (48%)
• Gaps: 58/304 - (19%)

Human     8 LLCLAGRALAAPQQEALPDETEVVEETVAEVTEVSVGANPVQVEVGEFDDGAEETEEE---VVAE 69
            ||.||..:....:::.:.|:                       |:||..|..:..||:   ..|:
 Worm     9 LLLLAASSFVDAKKKKIADD-----------------------ELGELLDNIDADEEKKSVEPAK 50

Human    70 NPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGE-FEKVCSNDNKTFDSSCHFFATKCTLE 133
            |||::|.|..||.|.:.:...|.|.|  .:.||...|: .:|||:|:|:||.|.|..:..:|..:
 Worm    51 NPCEDHQCGWGKECVVGKKGEPTCEC--ISKCPELDGDPMDKVCANNNQTFTSLCDLYRERCLCK 113

Human   134 GTKK------GHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQ 192
            ...|      ..|:||:|:|.||.:..|.:..:.:||.||.|||..|:..|.:|.|.:.|  |.:
 Worm   114 RKSKECSKAFNAKVHLEYLGECKKLDECTEEHMAQFPERMADWLFQVMKELKKRRELHKL--EWE 176

Human   193 KLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRA 257
            :|..:..:::||:                     :::||.|:|.:||..|.|..:||.||.|:.|
 Worm   177 ELLSEAENDDEKK---------------------HVYPVIWKFCELDTKPHDKSVSHHELIPITA 220

Human   258 PLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKQRYRQGSC 301
            |:||||.|...|.|.||.:||..|::.||..|.|:|:...|..|
 Worm   221 PVIPMESCIKPFLEGCDANNDGNISIKEWGKCLGLKEGEIQERC 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPARC	NP_001296373.1	FSL_SPARC	71..152	CDD:238649	31/87 (36%)
		EFh_SPARC_like	155..294	CDD:320010	48/138 (35%)
		EF-hand motif	227..260	CDD:320010	15/32 (47%)
		EF-hand motif	262..294	CDD:320010	14/31 (45%)
ost-1	NP_500039.1	FSL_SPARC	52..138	CDD:238649	31/87 (36%)
		EFh_SPARC_like	141..257	CDD:320010	48/138 (35%)
		EF-hand motif	190..223	CDD:320010	15/32 (47%)
		EF-hand motif	225..257	CDD:320010	14/31 (45%)