Protein Alignment SOX12 and HmgD

DIOPT Version :10

• Sequence 1: NP_008874.2
• Gene: SOX12 / 6666
• HGNCID: 11198
• Length: 315
• Species: Homo sapiens
• Sequence 2: NP_726109.1
• Gene: HmgD / 37481
• FlyBaseID: FBgn0004362
• Length: 112
• Species: Drosophila melanogaster
• Alignment Length: 132
• Identity: 35/132 - (26%)
• Similarity: 56/132 - (42%)
• Gaps: 27/132 - (20%)

Human    41 KRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADYP 105
            |||::|:|:|....|..|..:.|.:...|::||.|..|:.::|..      |.|....|...||
  Fly     6 KRPLSAYMLWLNSARESIKRENPGIKVTEVAKRGGELWRAMKDKS------EWEAKAAKAKDDY- 63

Human   106 DYKYRPRKKSKGAPAKARPRPPGGSGGGSRLKPGPQLPGRGGRRAAGGPLGGGAAAPEDDDEDDD 170
            |...:..:.:.|:.|      ..|.|...|.||..::..:..:              |:.|||||
  Fly    64 DRAVKEFEANGGSSA------ANGGGAKKRAKPAKKVAKKSKK--------------EESDEDDD 108

Human   171 EE 172
            :|
  Fly   109 DE 110

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SOX12	NP_008874.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..40
		HMG-box_SF	29..116	CDD:469606	21/74 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	100..288		17/73 (23%)
		Required for transcriptional activation activity and synergistic coactivation of transcriptional activity with POU3F2. /evidence=ECO:0000250|UniProtKB:Q04890	283..315
HmgD	NP_726109.1	HMG-box_SSRP1-like	7..71	CDD:438810	20/70 (29%)