Protein Alignment SOX15 and Sox100B

DIOPT Version :9

• Sequence 1: NP_008873.1
• Gene: SOX15 / 6665
• HGNCID: 11196
• Length: 233
• Species: Homo sapiens
• Sequence 2: NP_651839.1
• Gene: Sox100B / 45039
• FlyBaseID: FBgn0024288
• Length: 529
• Species: Drosophila melanogaster
• Alignment Length: 225
• Identity: 77/225 - (34%)
• Similarity: 101/225 - (44%)
• Gaps: 59/225 - (26%)

Human    37 SPAAPGTLPLEKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEE 101
            |..||.....|.:||||||||||:.|.||.|::|.|.:.|||:||.||..||.|.:.:|:||:|.
  Fly    65 SAKAPTDRKKEHIKRPMNAFMVWAQAARRVMSKQYPHLQNSELSKSLGKLWKNLKDSDKKPFMEF 129

Human   102 AKRLRARHLRDYPDYKYRPRRK------AKSSGAGPS------------RCGQGRGNLASGGPLW 148
            |::||..|.:::|||||:||||      ::.||.|.|            ..|:.|.:.::|....
  Fly   130 AEKLRMTHKQEHPDYKYQPRRKKARVLPSQQSGEGGSPGPEMTLSATMGSSGKPRSSNSNGQRRA 194

Human   149 GPGYATTQPSRGFGYRPPSYSTAYLPGSYGSSHCKLEA-----------------------PSPC 190
            |.|.|...    .|....:.|.|.: ||..|.....||                       .|||
  Fly   195 GKGNAAAD----LGSCASTISHANV-GSNSSDVFSNEAFMKSLNSACAASLMEQSLIETGLDSPC 254

Human   191 SLPQSDPRLQGELLPTYTHYLPPGSPTPYN 220
            |...|...|           .||.  ||||
  Fly   255 STASSMSSL-----------TPPA--TPYN 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SOX15	NP_008873.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48		3/10 (30%)
		Required to promote HAND1 transcriptional activator activity. /evidence=ECO:0000250|UniProtKB:P43267	1..47		3/9 (33%)
		SOX-TCF_HMG-box	48..119	CDD:238684	38/70 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	113..153		18/57 (32%)
		Interaction with FHL3. /evidence=ECO:0000250|UniProtKB:P43267	138..183		11/44 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	208..233		6/13 (46%)
Sox100B	NP_651839.1	SOX-TCF_HMG-box	76..146	CDD:238684	37/69 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148502
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.740