Protein Alignment SOX15 and Sox102F

DIOPT Version :10

• Sequence 1: NP_008873.1
• Gene: SOX15 / 6665
• HGNCID: 11196
• Length: 233
• Species: Homo sapiens
• Sequence 2: NP_001014695.1
• Gene: Sox102F / 43844
• FlyBaseID: FBgn0039938
• Length: 618
• Species: Drosophila melanogaster
• Alignment Length: 254
• Identity: 70/254 - (27%)
• Similarity: 105/254 - (41%)
• Gaps: 88/254 - (34%)

Human     5 GSSQDQAWSLEPPAATAAASSSSGPQEREGAGSPAAPGTLPLEK------------------VKR 51
            |::.:::.:|:|.:..   |...||       .||:|.:.||.:                  :||
  Fly   371 GTNSERSAALDPESLN---SGQLGP-------VPASPSSQPLRQGNGHGHGGNHGHVHSKPHIKR 425

Human    52 PMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDY 116
            ||||||||:..:||::.:..|.||||.|||.|||:||.:...:|:|:.||..||...|:..:|||
  Fly   426 PMNAFMVWAKDERRKILKACPDMHNSNISKILGARWKAMSNADKQPYYEEQSRLSKLHMEQHPDY 490

Human   117 KYRPR-----------------------RKAK-----------SSGAG---PSRCGQGRG----- 139
            :||||                       |:|:           |.|:|   ...|.:|.|
  Fly   491 RYRPRPKRTCIVDGKKMRISEYKVLMRNRRAEMRQLWCRTGGVSGGSGSLCADACPKGSGGSNSQ 555

Human   140 -------------NLASGGPLWGPGY-ATTQPSRGFGYRPPSYSTAYLPGSYGSSHCKL 184
                         ::||.......|: ....|.:.|.|.|.|.|    |..:.|...:|
  Fly   556 VAVAAAAAVYHLQDMASSAASTAHGHDCGHTPPQQFFYPPESLS----PSGFSSDEVEL 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SOX15	NP_008873.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48		11/42 (26%)
		Required to promote HAND1 transcriptional activator activity. /evidence=ECO:0000250|UniProtKB:P43267	1..47		10/41 (24%)
		HMG-box_SoxA_SoxB_SoxG	48..123	CDD:438837	39/115 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	113..153		18/95 (19%)
		Interaction with FHL3. /evidence=ECO:0000250|UniProtKB:P43267	138..183		12/63 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	208..233
Sox102F	NP_001014695.1	HMG-box_EGL13-like	421..498	CDD:438848	39/76 (51%)