Protein Alignment SOX3 and Sox3

DIOPT Version :10

• Sequence 1: NP_005625.2
• Gene: SOX3 / 6658
• HGNCID: 11199
• Length: 446
• Species: Homo sapiens
• Sequence 2: NP_001388121.1
• Gene: Sox3 / 679158
• RGDID: 1591839
• Length: 449
• Species: Rattus norvegicus
• Alignment Length: 450
• Identity: 416/450 - (92%)
• Similarity: 422/450 - (93%)
• Gaps: 5/450 - (1%)

Human     1 MRPVRENSSGARSPRVPADLARSILISLPFPPDSLAHRPPSSAPTESQGLFTVAAPAPGAPSPPA 65
            |||.|||:||.||||||||.|||...||||||:..|.||||:.||||.|||||||||||||||||
  Rat     1 MRPARENASGERSPRVPADFARSPSASLPFPPELPARRPPSATPTESPGLFTVAAPAPGAPSPPA 65

Human    66 TLAHLLPAPAMYSLLETELKNPVGTPTQAAGTGGPAAPGGAGKSSANAAGGANSGGGSSGGAS-- 128
            ||||||||||||||||||||||||.||.||.||||.|||.|||||||.|||||:|.|.||||:
  Rat    66 TLAHLLPAPAMYSLLETELKNPVGPPTPAAATGGPPAPGAAGKSSANPAGGANAGSGGSGGANGG 130

Human   129 --GGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDE 191
              |||||:|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 GGGGGGGSDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDE 195

Human   192 AKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPPGAAAAAAAAAAAAAAASSPVGVGQ 256
            |||||||||||||||||||||||||||||||||||.|||||| ||||||||||||||||||||||
  Rat   196 AKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPGGLLPPG-AAAAAAAAAAAAAASSPVGVGQ 259

Human   257 RLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPPMHRYDMAGLQYSPMMPPGAQSYM 321
            |||||||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||
  Rat   260 RLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPQMHRYDMAGLQYSPMMPPGAQSYM 324

Human   322 NVAAAAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAIA 386
            |.|||||||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||
  Rat   325 NAAAAAAAASGYGGMAPSAAAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAIA 389

Human   387 SHSQRACLGDLRDMISMYLPPGGDAADAASPLPGGRLHGVHQHYQGAGTAVNGTVPLTHI 446
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   390 SHSQRACLGDLRDMISMYLPPGGDAADAASPLPGGRLHGVHQHYQGAGTAVNGTVPLTHI 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SOX3	NP_005625.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..48		12/18 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	87..140		41/56 (73%)
		HMG-box_SoxB	137..212	CDD:438790	74/74 (100%)
		SOXp	208..302	CDD:463537	90/93 (97%)
		9aaTAD. /evidence=ECO:0000269|PubMed:34342803	399..407		7/7 (100%)
Sox3	NP_001388121.1	HMG-box_SoxA_SoxB_SoxG	142..216	CDD:438837	73/73 (100%)
		SOXp	212..305	CDD:463537	90/93 (97%)