Protein Alignment SOX3 and Sox3

DIOPT Version :10

• Sequence 1: NP_005625.2
• Gene: SOX3 / 6658
• HGNCID: 11199
• Length: 446
• Species: Homo sapiens
• Sequence 2: NP_033263.2
• Gene: Sox3 / 20675
• MGIID: 98365
• Length: 450
• Species: Mus musculus
• Alignment Length: 451
• Identity: 415/451 - (92%)
• Similarity: 421/451 - (93%)
• Gaps: 6/451 - (1%)

Human     1 MRPVRENSSGARSPRVPADLARSILISLPFPPDSLAHRPPSSAPTESQGLFTVAAPAPGAPSPPA 65
            |||.|||:||.||||||||.|||...||||||:..|.||.|:.||||.|||||||||||||||||
Mouse     1 MRPARENASGERSPRVPADFARSPSASLPFPPELPARRPLSTTPTESPGLFTVAAPAPGAPSPPA 65

Human    66 TLAHLLPAPAMYSLLETELKNPVGTPTQAAGTGGPAAPGGAGKSSANAAGGANSGGGSSGGAS-- 128
            ||||||||||||||||||||||||.||.|||||.|||||.||||.||.|||||:|.|.||||:
Mouse    66 TLAHLLPAPAMYSLLETELKNPVGPPTPAAGTGVPAAPGAAGKSGANPAGGANAGNGGSGGANGG 130

Human   129 ---GGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFID 190
               |||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 GGGGGGGGSDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFID 195

Human   191 EAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPPGAAAAAAAAAAAAAAASSPVGVG 255
            ||||||||||||||||||||||||||||||||||||.|||||| |||||||||||||||||||||
Mouse   196 EAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPGGLLPPG-AAAAAAAAAAAAAASSPVGVG 259

Human   256 QRLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPPMHRYDMAGLQYSPMMPPGAQSY 320
            ||||||||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||
Mouse   260 QRLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPQMHRYDMAGLQYSPMMPPGAQSY 324

Human   321 MNVAAAAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAI 385
            ||.|||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||
Mouse   325 MNAAAAAAAASGYGGMAPSAAAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAI 389

Human   386 ASHSQRACLGDLRDMISMYLPPGGDAADAASPLPGGRLHGVHQHYQGAGTAVNGTVPLTHI 446
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   390 ASHSQRACLGDLRDMISMYLPPGGDAADAASPLPGGRLHGVHQHYQGAGTAVNGTVPLTHI 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SOX3	NP_005625.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..48		11/18 (61%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	87..140		41/57 (72%)
		HMG-box_SoxB	137..212	CDD:438790	74/74 (100%)
		SOXp	208..302	CDD:463537	90/93 (97%)
		9aaTAD. /evidence=ECO:0000269|PubMed:34342803	399..407		7/7 (100%)
Sox3	NP_033263.2	HMG-box_SoxA_SoxB_SoxG	143..217	CDD:438837	73/73 (100%)
		SOXp	213..306	CDD:463537	90/93 (97%)