Protein Alignment SOX2 and Sox102F

DIOPT Version :10

• Sequence 1: NP_003097.1
• Gene: SOX2 / 6657
• HGNCID: 11195
• Length: 317
• Species: Homo sapiens
• Sequence 2: NP_001014695.1
• Gene: Sox102F / 43844
• FlyBaseID: FBgn0039938
• Length: 618
• Species: Drosophila melanogaster
• Alignment Length: 207
• Identity: 69/207 - (33%)
• Similarity: 97/207 - (46%)
• Gaps: 50/207 - (24%)

Human    11 PPGPQQTSGGGGGNSTAAAAGGN--QKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISK 73
            |.......|.|.|:      |||  ..:|...:||||||||||::.:|||:.:..|.||||.|||
  Fly   397 PSSQPLRQGNGHGH------GGNHGHVHSKPHIKRPMNAFMVWAKDERRKILKACPDMHNSNISK 455

Human    74 RLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKT--------------KTLMK--- 121
            .|||.||.:|..:|:|:.:|..||..|||::||||:||||.|.              |.||:
  Fly   456 ILGARWKAMSNADKQPYYEEQSRLSKLHMEQHPDYRYRPRPKRTCIVDGKKMRISEYKVLMRNRR 520

Human   122 ---KDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYA-----HMNGWSNGSYSMMQDQL 178
               :..:...||:....|:..|.....|:|   |.|.::...|     |:...::.:.|
  Fly   521 AEMRQLWCRTGGVSGGSGSLCADACPKGSG---GSNSQVAVAAAAAVYHLQDMASSAAS------ 576

Human   179 GYPQHPGLNAHG 190
                    .|||
  Fly   577 --------TAHG 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SOX2	NP_003097.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43		8/33 (24%)
		HMG-box_SoxB	39..118	CDD:438790	44/92 (48%)
		SOXp	110..200	CDD:463537	22/106 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	243..266
		9aaTAD. /evidence=ECO:0000250|UniProtKB:P41225	272..280
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..317
Sox102F	NP_001014695.1	HMG-box_EGL13-like	421..498	CDD:438848	43/76 (57%)