Protein Alignment SOX1 and Sox100B

DIOPT Version :9

• Sequence 1: NP_005977.2
• Gene: SOX1 / 6656
• HGNCID: 11189
• Length: 391
• Species: Homo sapiens
• Sequence 2: NP_651839.1
• Gene: Sox100B / 45039
• FlyBaseID: FBgn0024288
• Length: 529
• Species: Drosophila melanogaster
• Alignment Length: 510
• Identity: 119/510 - (23%)
• Similarity: 170/510 - (33%)
• Gaps: 234/510 - (45%)

Human    44 AKANQDR----VKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEA 104
            |||..||    :||||||||||::..||.|:::.|.:.|||:||.||..||.:.:::|:||::.|
  Fly    66 AKAPTDRKKEHIKRPMNAFMVWAQAARRVMSKQYPHLQNSELSKSLGKLWKNLKDSDKKPFMEFA 130

Human   105 KRLRALHMKEHPDYKYRPRRKTKTLLKKD----------KYSLAGGLLAAG------------AG 147
            ::||..|.:|||||||:||||...:|...          :.:|:..:.::|            ||
  Fly   131 EKLRMTHKQEHPDYKYQPRRKKARVLPSQQSGEGGSPGPEMTLSATMGSSGKPRSSNSNGQRRAG 195

Human   148 GGGAAVAMG-------------------------------------------------------- 156
            .|.||..:|
  Fly   196 KGNAAADLGSCASTISHANVGSNSSDVFSNEAFMKSLNSACAASLMEQSLIETGLDSPCSTASSM 260

Human   157 --------------------------------------VGVGVGA--------AAVGQ---RLES 172
                                                  .|.|.|.        .|:|:   :.:|
  Fly   261 SSLTPPATPYNVAPSNAKASAANNPSLLLRQLSEPVANAGDGYGVLLEAGREYVAIGEVNYQGQS 325

Human   173 PG---GAAGGG-------YAHVNGWANGAYPGSVAAAAA----------AAAMMQEAQL-----A 212
            .|   ||.|||       ..::||:  |.|.||..:..|          |....|:.|.     |
  Fly   326 AGVQSGAEGGGAGQEMDFLENINGY--GGYTGSRVSYPAYSYPANGGHFATEEQQQQQALQASEA 388

Human   213 YGQHPGAGGAHP----------------HAHPAHPHP-HHPHAHPHNPQPMHRYDMGALQYSPIS 260
            ....|.|....|                |.||.|.|| |||                 |.:||..
  Fly   389 LNYKPAAADIDPKEIDQYFMDQMLPMTQHHHPHHTHPLHHP-----------------LHHSPPL 436

Human   261 NSQGYMSASPSGYGGLPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGS 325
            ||...:|:           |.::|::....|.....:..:.||::||            ..|:..
  Fly   437 NSSASLSS-----------ACSSASSQQPVAEYYEHLGYSPAASSAS------------QNPNFG 478

Human   326 PPAP----AHSRAPCPGDLREMISMYLPAGEGGDPAAAAAAAAQSRLHSLP-QHY 375
            |..|    |.|..|..||         ||     |.....:..|.:.|..| ||:
  Fly   479 PQQPYANGAASMTPTLGD---------PA-----PQQELQSQQQEQQHQNPSQHH 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SOX1	NP_005977.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		5/11 (45%)
		SOX-TCF_HMG-box	50..121	CDD:238684	37/74 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..249		12/51 (24%)
Sox100B	NP_651839.1	SOX-TCF_HMG-box	76..146	CDD:238684	35/69 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810