Protein Alignment SORD and XYL2

DIOPT Version :10

• Sequence 1: NP_003095.2
• Gene: SORD / 6652
• HGNCID: 11184
• Length: 357
• Species: Homo sapiens
• Sequence 2: NP_013171.1
• Gene: XYL2 / 850759
• SGDID: S000004060
• Length: 356
• Species: Saccharomyces cerevisiae
• Alignment Length: 333
• Identity: 148/333 - (44%)
• Similarity: 214/333 - (64%)
• Gaps: 10/333 - (3%)

Human    11 SLVVHGPGDLRLENYPIPE-PGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASG 74
            ::|:..||.:.|.|..||: ..||||::::.:.||||||:||:.:|||.|::|:.|||||||:||
Yeast     9 AIVLERPGKITLTNVSIPKISDPNEVIIQIKATGICGSDIHYYTHGRIANYVVESPMVLGHESSG 73

Human    75 TVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAF 139
            .|..:|.:||.||.|||||:|||.|.......|.|||||.|::.|.||||.||.|.::||....|
Yeast    74 IVALIGENVKTLKVGDRVALEPGIPDRFSPEMKEGRYNLDPNLKFAATPPFDGTLTKYYKTMKDF 138

Human   140 CYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTD 204
            .|||||:|:||||||||||||.|||.:...:..|.:.:|.||||||::...||...|||.||..|
Yeast   139 VYKLPDDVSFEEGALIEPLSVAIHANKLAKIKFGARCVVFGAGPIGLLAGKVASVFGAADVVFVD 203

Human   205 LSATRLSKAKEIGADLVLQISKESP-----QEIARKVEGQLGCKPEVTIECTGAEASIQAGIYAT 264
            |...:|..|::.||..::. |.:.|     ..:.:|..|:.|.  :|..||:|||..::|||...
Yeast   204 LLENKLETARQFGATHIVN-SGDLPHGVTVDSVIKKAIGKKGA--DVVFECSGAEPCVRAGIEVC 265

Human   265 RSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYC-NTWPVAISMLASKSVNVKPLVTHRFPL 328
            ::||.:|.||:|.|....|:.....:|:..:|.|||| ..:..:|.:::|:.:::||.:|||:..
Yeast   266 KAGGTIVQVGMGQEEIQFPISIIPTKELTFQGCFRYCQGDYSDSIELVSSRKLSLKPFITHRYSF 330

Human   329 EKALEAFE 336
            :.|:||||
Yeast   331 KDAVEAFE 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SORD	NP_003095.2	sorbitol_DH	11..350	CDD:176188	148/333 (44%)
XYL2	NP_013171.1	sorbitol_DH	9..354	CDD:176188	148/333 (44%)