Protein Alignment SNTB1 and sntb1

DIOPT Version :10

• Sequence 1: XP_054217035.1
• Gene: SNTB1 / 6641
• HGNCID: 11168
• Length: 636
• Species: Homo sapiens
• Sequence 2: XP_012820630.1
• Gene: sntb1 / 100493340
• XenbaseID: XB-GENE-1013041
• Length: 509
• Species: Xenopus tropicalis
• Alignment Length: 541
• Identity: 387/541 - (71%)
• Similarity: 440/541 - (81%)
• Gaps: 35/541 - (6%)

Human    99 MAVAAAAAAAGPAGAGGGRAQRSGLLEVLVRDRWHKVLVNLSEDALVLSS---EEGAAAYNGIGT 160
            ||||||.|.            |||.||||||.||||||.||.|.:|||||   .|.|.:.|.:..
 Frog     1 MAVAAAGAL------------RSGWLEVLVRGRWHKVLGNLYESSLVLSSPERPEDAPSSNSMTN 53

Human   161 ATNGSFCRGAGAGHPGAGGAQPPDSPAGVRTAFTDLPEQVPESISNQKRGVKVLKQELGGLGISI 225
            .||                    .||.|||||||:||:.|||:|:|:||.|||:|||||||||||
 Frog    54 GTN--------------------SSPQGVRTAFTELPDTVPEAIANKKRAVKVVKQELGGLGISI 98

Human   226 KGGKENKMPILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGKEVLLEVK 290
            |||||||||||||||||||||||||:||||||||:|||.|||||||||||||||:||:||:||||
 Frog    99 KGGKENKMPILISKIFKGLAADQTQSLYVGDAILTVNGLDLRDATHDEAVQALKKAGREVILEVK 163

Human   291 YMREATPYVKKGSPVSEIGWETPPPESPRLGGSTSDPPSSQSFSFHRDRKSIPLKMCYVTRSMAL 355
            |||||||||||||||||||||||||||||||.::..|||..:.|.|.||||||||||||||||.:
 Frog   164 YMREATPYVKKGSPVSEIGWETPPPESPRLGNTSVCPPSPVALSIHGDRKSIPLKMCYVTRSMTV 228

Human   356 ADPENRQLEIHSPDAKHTVILRSKDSATAQAWFSAIHSNVNDLLTRVIAEVREQLGKTGIAGSRE 420
            .|||||.||:|||||||||:|||.|..||||||:||||..:||::|||.||:||||||||:||.:
 Frog   229 PDPENRNLELHSPDAKHTVVLRSSDPVTAQAWFNAIHSAASDLVSRVITEVKEQLGKTGISGSTD 293

Human   421 IRHLGWLAEKVPGESKKQWKPALVVLTEKDLLIYDSMPRRKEAWFSPVHTYPLLATRLVHSGPGK 485
            |.|||||||||.||::|.||..|:||||||||:||||||.|:||.:|||.|||:|||||||||||
 Frog   294 IGHLGWLAEKVLGENEKHWKAVLMVLTEKDLLMYDSMPRMKDAWLNPVHAYPLIATRLVHSGPGK 358

Human   486 GSPQAGVDLSFATRTGTRQGIETHLFRAETSRDLSHWTRSIVQGCHNSAELIAEISTACTYKNQE 550
            .|...|.:.|||||||::||||||.|||||:||||.||||||||||:||||:.||||.|||||.|
 Frog   359 ISSLPGTEFSFATRTGSKQGIETHFFRAETNRDLSLWTRSIVQGCHHSAELVKEISTPCTYKNNE 423

Human   551 CRLTIHYENGFSITTEPQEGAFPKTIIQSPYEKLKMSSDDGIRMLYLDFGGKDGEIQLDLHSCPK 615
            |||.|:|::||.:|:|..:|.:.:.::|.||||||||||||::||||||||||||:|||||.|||
 Frog   424 CRLVINYDHGFLLTSEALDGTYSRPLLQFPYEKLKMSSDDGVKMLYLDFGGKDGELQLDLHCCPK 488

Human   616 PIVFIIHSFLSAKITRLGLVA 636
            |||||||||||||||||||||
 Frog   489 PIVFIIHSFLSAKITRLGLVA 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SNTB1	XP_054217035.1	PDZ_syntrophin-like	209..291	CDD:467262	73/81 (90%)
		PHsplit_syntrophin	<340..397	CDD:269960	44/56 (79%)
		PH	421..531	CDD:459697	82/109 (75%)
sntb1	XP_012820630.1	PDZ_syntrophin-like	82..164	CDD:467262	73/81 (90%)
		PHsplit_syntrophin	<205..270	CDD:269960	48/64 (75%)
		PH	296..404	CDD:459697	81/107 (76%)