Protein Alignment SNTA1 and snta1

DIOPT Version :10

• Sequence 1: NP_003089.1
• Gene: SNTA1 / 6640
• HGNCID: 11167
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_001072684.1
• Gene: snta1 / 780141
• XenbaseID: XB-GENE-962569
• Length: 473
• Species: Xenopus tropicalis
• Alignment Length: 503
• Identity: 315/503 - (62%)
• Similarity: 372/503 - (73%)
• Gaps: 32/503 - (6%)

Human     1 MASGRRAPRTGLLELRAGAGSGAGGERWQRVLLSLAEDVLTVSPADGDPGPEPGAPREQEPAQLN 65
            |||...|.|:||||||      ..||||.||||.|.|:.:|.:|.     |||||..|:   .||
 Frog     1 MASPGTAHRSGLLELR------CPGERWVRVLLLLGEETVTFTPE-----PEPGAAEEK---ALN 51

Human    66 GAAEPGAGPPQLPEALLLQRRRVTVRKADAGGLGISIKGGRENKMPILISKIFKGLAADQTEALF 130
            | |||..|   :||:|:..||.|.|.|.||||||:||||||||||||||||||||||||.|.:|:
 Frog    52 G-AEPAGG---VPESLINLRRTVRVLKQDAGGLGVSIKGGRENKMPILISKIFKGLAADLTGSLY 112

Human   131 VGDAILSVNGEDLSSATHDEAVQVLKKTGKEVVLEVKYMKDVSPYFKNSTGGTSVGWDSPPASPL 195
            ||||||||||.|||.||||:|||.||||||||||||||||::|||||.|....|      ||:||
 Frog   113 VGDAILSVNGVDLSEATHDDAVQALKKTGKEVVLEVKYMKEISPYFKGSPPSGS------PAAPL 171

Human   196 QRQPSSPGPTPRNFSEAKHMSLKMAYVSKRCTPNDPEPRYLEICSADGQDTLFLRAKDEASARSW 260
            |:: .||...|:.:.:.|.:.|||.|||:|..|.|.||||||||||||:|.||.|||||.:|:||
 Frog   172 QKR-GSPALPPKEYKDGKSIPLKMCYVSRRFLPTDTEPRYLEICSADGRDVLFFRAKDEGTAQSW 235

Human   261 ATAIQAQVNTLTPRVKDELQALLAATSTAGSQDIKQIGWLTEQLPSGGTAPTLALLTEKELLLYL 325
            ..||....:.|.|||:::::.||       .:||||:||||||||..|....|||||||:||||.
 Frog   236 FNAIHTNASALAPRVREDVKQLL-------GKDIKQMGWLTEQLPQDGKRNLLALLTEKDLLLYN 293

Human   326 SLPETREALSRPARTAPLIATRLVHSGPSKGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELA 390
            |||.:||..|:||...||||||||||||||.|..||.||:||||:||:.||:|||||||:.:|||
 Frog   294 SLPHSREGFSKPAYCHPLIATRLVHSGPSKSSPLYDTELAFALRSGTQKGVETHLFSVETQRELA 358

Human   391 AWTRQLVDGCHRAAEGVQEVSTACTWNGRPCSLSVHIDKGFTLWAAEPGAARAVLLRQPFEKLQM 455
            .|||.||||||.|||.::||:|||||.|..|:||:|||:||||:..|||..:.:...||||||:|
 Frog   359 TWTRVLVDGCHSAAELIKEVTTACTWGGNECALSIHIDQGFTLFTEEPGLNKVIHFHQPFEKLRM 423

Human   456 SSDDGASLLFLDFGGAEGEIQLDLHSCPKTIVFIIHSFLSAKVTRLGL 503
            |||||..:|:|:||..|.|:|||||||||||||||||||||||:||||
 Frog   424 SSDDGVRILYLEFGNPEAELQLDLHSCPKTIVFIIHSFLSAKVSRLGL 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SNTA1	NP_003089.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		11/23 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	40..77		15/36 (42%)
		PDZ_syntrophin-like	86..168	CDD:467262	68/81 (84%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	180..210		9/29 (31%)
		PHsplit_syntrophin	<209..270	CDD:269960	35/60 (58%)
		PH	298..401	CDD:459697	72/102 (71%)
		Calmodulin-binding. /evidence=ECO:0000250	483..505		20/21 (95%)
snta1	NP_001072684.1	PDZ_syntrophin-like	68..150	CDD:467262	68/81 (84%)
		PHsplit_syntrophin	<188..245	CDD:269960	35/56 (63%)
		PH	262..369	CDD:459697	75/106 (71%)