Protein Alignment SNTA1 and snta1

DIOPT Version :10

• Sequence 1: NP_003089.1
• Gene: SNTA1 / 6640
• HGNCID: 11167
• Length: 505
• Species: Homo sapiens
• Sequence 2: XP_073810883.1
• Gene: snta1 / 100332905
• ZFINID: ZDB-GENE-120919-5
• Length: 479
• Species: Danio rerio
• Alignment Length: 510
• Identity: 277/510 - (54%)
• Similarity: 354/510 - (69%)
• Gaps: 36/510 - (7%)

Human     1 MASGRRAPRTGLLELRAGAGSGAGGERWQRVLLSLAEDVLTVSPAD-----GDPGPEPGAPREQE 60
            ||:..:..::||||||...      ..|.|||.:|..|..||||.:     ....|.|||....:
Zfish     1 MAAAVKPVKSGLLELRVTV------HHWIRVLATLTGDTFTVSPGETAEESASNSPAPGAAVNGD 59

Human    61 PAQLNGAAEPGAGPPQLPEALLLQRRRVTVRKADAGGLGISIKGGRENKMPILISKIFKGLAADQ 125
            ||.|:      |.|  :|:.:...:|.|.|.|.:.||||||||||:|||||||||||||||||||
Zfish    60 PANLS------ASP--VPDTITNVKRTVRVTKQEVGGLGISIKGGKENKMPILISKIFKGLAADQ 116

Human   126 TEALFVGDAILSVNGEDLSSATHDEAVQVLKKTGKEVVLEVKYMKDVSPYFKNSTGGTSVGWDSP 190
            ||||:||||||||||.||..||||||||.||||||||:|||||:|::|.:||..:.|..| .|||
Zfish   117 TEALYVGDAILSVNGNDLREATHDEAVQALKKTGKEVILEVKYIKEMSAFFKGGSTGPPV-LDSP 180

Human   191 PASPLQRQPSSPGPTPRNFSEAKHMSLKMAYVSKRCTPNDPEPRYLEICSADGQDTLFLRAKDEA 255
            ||:| |:|      |.....|.:.:.|:|.:|:::..|.|||.||.|:.|:|.:.::||||||.|
Zfish   181 PATP-QKQ------TDPALKETRTIPLRMCHVTRKQCPPDPEDRYFEVVSSDRKTSVFLRAKDHA 238

Human   256 SARSWATAIQAQVNTLTPRVKDELQALLAATSTAGSQDIKQIGWLTEQLPSGGTAPTLALLTEKE 320
            .|::|..:||:....|....||||:.|      ..|.:|..|||:.||   |...|.||:||:::
Zfish   239 MAQAWYNSIQSSSAALLNTAKDELKTL------QPSLNIIHIGWIIEQ---GSERPILAVLTDRD 294

Human   321 LLLYLSLPETREALSRPARTAPLIATRLVHSGPSKGSVPYDAELSFALRTGTRHGVDTHLFSVES 385
            ||||.:||:::|.|:.|.::.|||.||||||||.|.|..:|:||:|.||.||:.||:||||.|:|
Zfish   295 LLLYGALPDSKETLNSPDKSYPLITTRLVHSGPGKSSSVHDSELTFGLRLGTKQGVETHLFRVDS 359

Human   386 PQELAAWTRQLVDGCHRAAEGVQEVSTACTWNGRPCSLSVHIDKGFTLWAAEPGAARAVLLRQPF 450
            .::|:.||..||||||.|||.||||.|||:|||:.|.||||||:||:|:..:.|..::|||:|||
Zfish   360 AKDLSCWTHLLVDGCHSAAELVQEVITACSWNGKSCMLSVHIDRGFSLFMEDCGVKKSVLLQQPF 424

Human   451 EKLQMSSDDGASLLFLDFGGAEGEIQLDLHSCPKTIVFIIHSFLSAKVTRLGLLA 505
            |:|:||||||..::||||||.:.||||||||||||:||||||||||||.||||||
Zfish   425 ERLRMSSDDGVRMIFLDFGGPDAEIQLDLHSCPKTMVFIIHSFLSAKVKRLGLLA 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SNTA1	NP_003089.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		8/23 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	40..77		13/41 (32%)
		PDZ_syntrophin-like	86..168	CDD:467262	68/81 (84%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	180..210		11/29 (38%)
		PHsplit_syntrophin	<209..270	CDD:269960	24/60 (40%)
		PH	298..401	CDD:459697	55/102 (54%)
		Calmodulin-binding. /evidence=ECO:0000250	483..505		19/21 (90%)
snta1	XP_073810883.1	None