DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Chmp4c and CG5498

DIOPT Version :9

Sequence 1:	NP_079795.1	Gene:	Chmp4c / 66371	MGIID:	1913621	Length:	232	Species:	Mus musculus
Sequence 2:	NP_730525.2	Gene:	CG5498 / 40250	FlyBaseID:	FBgn0027565	Length:	448	Species:	Drosophila melanogaster

Alignment Length:	154	Identity:	37/154 - (24%)
Similarity:	70/154 - (45%)	Gaps:	3/154 - (1%)

- Green bases have known domain annotations that are detailed below.

Mouse    24 EALARLRETEEMLAKKQEYLENRIQRELALAKKHGSQNKRAALQALKRKKR-FEKQLTQVDGTLS 87
            :|:..|:.|:..|.|:.|.||..|:......:::..:|||...:...||:. .||...:....|.
  Fly   244 QAVHNLQNTQAQLLKQLEDLEEEIKVNDDKVRQYMKENKRQMAKTYLRKRHLLEKNHERRSLALH 308

Mouse    88 TIEFQREALENSHTNTEVLRNMGFAAKAMKAVHDNMDL--NKIDDLMQDITEQQDIAQEISEAFS 150
            .||....:::.:..:..||......:..:|.|..|..|  :.:|:::.|:.:..|..:|:.:..|
  Fly   309 NIESLLSSVDEAQNSGVVLDAYKIGSNTLKKVLSNSGLKYDNVDEVLADVRDTLDQHREVQDIMS 373

Mouse   151 QRVQFADGFDEAELLAELEELEQE 174
            ..|......::.:|..||.||..|
  Fly   374 NSVVENASQEDDQLEQELRELAGE 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chmp4c	NP_079795.1	Intramolecular interaction with C-terminus. /evidence=ECO:0000250	1..153		30/131 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23
		Snf7	24..190	CDD:281366	37/154 (24%)
		Intramolecular interaction with N-terminus. /evidence=ECO:0000250	154..232		6/21 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	177..232
CG5498	NP_730525.2	Snf7	244..397	CDD:304451	36/152 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22761
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010