Protein Alignment SNRPA1 and Mapmodulin

DIOPT Version :10

• Sequence 1: NP_003081.2
• Gene: SNRPA1 / 6627
• HGNCID: 11152
• Length: 255
• Species: Homo sapiens
• Sequence 2: NP_001097361.1
• Gene: Mapmodulin / 37043
• FlyBaseID: FBgn0034282
• Length: 363
• Species: Drosophila melanogaster
• Alignment Length: 290
• Identity: 68/290 - (23%)
• Similarity: 102/290 - (35%)
• Gaps: 97/290 - (33%)

Human     9 IEQAAQYTNAVRDRELD-LRGYKIPVIENLGATLDQFDAID---FSDNEIRKLDGFPLLRRLKTL 69
            :|:.|:..|.:.:..|| .|...|     :|.| |::.|::   ..:..:..|.|||.|..||.|
  Fly     7 LERRARKVNQITELNLDNCRSTSI-----VGLT-DEYTALESLSLINVGLTTLKGFPKLPNLKKL 65

Human    70 LVNNNRICRIGEGLD--QALPCLTELILTNNSLVELGDLDPLASLKSLTYLSILRNPVTNKKHYR 132
            .:::|   ||..||:  ...|.|..|.|:.|.:.:|..|.||...|:|..|.:..|..|...:||
  Fly    66 ELSDN---RISSGLNYLTTSPKLQYLNLSGNKIKDLETLKPLEEFKNLVVLDLFNNDATQVDNYR 127

Human   133 LYVIYKVPQVRVLD-FQ------------------------------------KVKLKERQEAEK 160
            ..:...:|.:..|| |.                                    ::.|.|.:..||
  Fly   128 EKIFKMLPSLNFLDGFDCNDEEVQSDGDDDDEVNGNDSDEVGDKCNAFCLNGLEIDLDELEAFEK 192

Human   161 MFKGKRGAQLAKDIARRSKTFNPGAGLPTDKKKGGPSPGDVEAIKNAIANASTLAEVERLKGLLQ 225
            ..|.|:..|                    ||    |.|            .|...||:.|...|:
  Fly   193 RVKAKKSLQ--------------------DK----PPP------------QSEDKEVDELDEYLK 221

Human   226 SGQIPGRERRSGPTDDGEEEMEEDTVTNGS 255
            ..|:  ||.....||       |.:|.|.:
  Fly   222 ELQL--RESTDASTD-------EQSVINAT 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SNRPA1	NP_003081.2	LRR_9	1..175	CDD:405295	51/208 (25%)
		LRR 1	20..41		5/21 (24%)
		leucine-rich repeat	22..43	CDD:275378	6/21 (29%)
		LRR 2	43..64		5/23 (22%)
		leucine-rich repeat	44..65	CDD:275378	6/23 (26%)
		LRR 3	65..86		8/22 (36%)
		leucine-rich repeat	66..89	CDD:275378	8/24 (33%)
		LRR 4	89..110		7/20 (35%)
		leucine-rich repeat	90..114	CDD:275378	8/23 (35%)
		leucine-rich repeat	115..127	CDD:275378	3/11 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..201		4/26 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	222..255		9/32 (28%)
Mapmodulin	NP_001097361.1	PPP1R42	15..142	CDD:455733	40/135 (30%)
		leucine-rich repeat	17..39	CDD:275380	7/27 (26%)
		leucine-rich repeat	40..61	CDD:275380	5/20 (25%)
		leucine-rich repeat	62..84	CDD:275380	8/24 (33%)
		leucine-rich repeat	85..109	CDD:275380	8/23 (35%)
		leucine-rich repeat	110..136	CDD:275380	6/25 (24%)