Protein Alignment SNCA and Snca

DIOPT Version :10

• Sequence 1: XP_011530505.1
• Gene: SNCA / 6622
• HGNCID: 11138
• Length: 170
• Species: Homo sapiens
• Sequence 2: NP_033247.1
• Gene: Snca / 20617
• MGIID: 1277151
• Length: 140
• Species: Mus musculus
• Alignment Length: 117
• Identity: 102/117 - (87%)
• Similarity: 106/117 - (90%)
• Gaps: 4/117 - (3%)

Human     1 MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTN 65
            ||||||||||||||||||||||||||||||||||||||||||||||||||||.||||||||||||
Mouse     1 MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVTTVAEKTKEQVTN 65

Human    66 VGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKKHPKYKPSKRQENVV 117
            |||||||||||||||||||||:||||||||||||:||....|.    ||.::
Mouse    66 VGGAVVTGVTAVAQKTVEGAGNIAAATGFVKKDQMGKGEEGYP----QEGIL 113

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SNCA	XP_011530505.1	Synuclein	1..>105	CDD:460186	99/103 (96%)
Snca	NP_033247.1	Synuclein	1..131	CDD:460186	102/117 (87%)
		4 X 11 AA tandem repeats of [EGS]-K-T-K-[EQ]-[GQ]-V-X(4)	20..67		45/46 (98%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	99..140		6/19 (32%)
		Interaction with SERF1A. /evidence=ECO:0000250|UniProtKB:P37840	111..140		0/3 (0%)