Protein Alignment SMN1 and spf30

DIOPT Version :10

• Sequence 1: XP_047273571.1
• Gene: SMN1 / 6606
• HGNCID: 11117
• Length: 295
• Species: Homo sapiens
• Sequence 2: NP_588166.1
• Gene: spf30 / 2538711
• PomBaseID: SPCC1281.02C
• Length: 311
• Species: Schizosaccharomyces pombe
• Alignment Length: 156
• Identity: 35/156 - (22%)
• Similarity: 54/156 - (34%)
• Gaps: 60/156 - (38%)

Human    95 GDKCSAIW-SEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPICEVAN--NI---- 152
            |:...|.| |.|...||:.|.::           :|:|..::..:..|..|..|..:  :|
pombe    80 GNLVMARWVSGDYLFYPSRITAV-----------SGFGANKKYTVQFLDYPDIETVSLKHIKAMP 133

Human   153 EQNAQENENESQV------------------------STDES---ENSRSPGNKSD-----NIKP 185
            |:..||.|...::                        ||..|   ..:.||..||.     |:.|
pombe   134 EEKRQEIEGNKEILKKSTTIRSTPVREPTKAISVASMSTSPSNYASRASSPDMKSSAAVTANVSP 198

Human   186 --------KSAPWNSFLPP--PPPMP 201
                    .:.|..|.:||  |||:|
pombe   199 IQNVAQHVSTLPKISPIPPSNPPPVP 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMN1	XP_047273571.1	SMN	26..291	CDD:428716	35/156 (22%)
spf30	NP_588166.1	Tudor_SpSPF30-like	77..132	CDD:410517	14/62 (23%)