Protein Alignment SMARCD1 and Smarcd1

DIOPT Version :10

• Sequence 1: NP_003067.3
• Gene: SMARCD1 / 6602
• HGNCID: 11106
• Length: 515
• Species: Homo sapiens
• Sequence 2: NP_114030.2
• Gene: Smarcd1 / 83797
• MGIID: 1933623
• Length: 515
• Species: Mus musculus
• Alignment Length: 515
• Identity: 512/515 - (99%)
• Similarity: 514/515 - (99%)
• Gaps: 0/515 - (0%)

Human     1 MAARAGFQSVAPSGGAGASGGAGAAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYPRPGMLP 65
            |||||||||||||||||||||||.|||||||||||||||||||||||||||||||||||||||||
Mouse     1 MAARAGFQSVAPSGGAGASGGAGVAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYPRPGMLP 65

Human    66 GSRMTPQGPSMGPPGYGGNPSVRPGLAQSGMDQSRKRPAPQQIQQVQQQAVQNRNHNAKKKKMAD 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 GSRMTPQGPSMGPPGYGGNPSVRPGLAQSGMDQSRKRPAPQQIQQVQQQAVQNRNHNAKKKKMAD 130

Human   131 KILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKRKLRIFISNTFNPAKS 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 KILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKRKLRIFISNTFNPAKS 195

Human   196 DAEDGEGTVASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHR 260
            |||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||
Mouse   196 DAEDGEGTVASWELRVEGRLLEDAALSKYDATKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHR 260

Human   261 TATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPRLARLLGIHTQTRPVIIQALWQYIKT 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 TATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPRLARLLGIHTQTRPVIIQALWQYIKT 325

Human   326 HKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQRLHALLMPPEPIIINHVISVDPNDQKKTACY 390
            ||||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   326 HKLQDPHEREFVLCDKYLQQIFESQRMKFSEIPQRLHALLMPPEPIIINHVISVDPNDQKKTACY 390

Human   391 DIDVEVDDTLKTQMNSFLLSTASQQEIATLDNKIHETIETINQLKTQREFMLSFARDPQGFINDW 455
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   391 DIDVEVDDTLKTQMNSFLLSTASQQEIATLDNKIHETIETINQLKTQREFMLSFARDPQGFINDW 455

Human   456 LQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT 515
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   456 LQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMARCD1	NP_003067.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..103		100/101 (99%)
		Interaction with ESR1, NR1H4, NR3C1, PGR and SMARCA4. /evidence=ECO:0000269|PubMed:12917342	43..167		123/123 (100%)
		Interaction with SMARCC1 and SMARCC2. /evidence=ECO:0000269|PubMed:12917342	168..474		303/305 (99%)
		Necessary for GR/NR3C1-mediated remodeling and transcription from chromatin, required for GR/NR3C1 interaction with the BRG1/SMARCA4 complex in vivo	180..515		332/334 (99%)
		SWIB_BAF60A	294..370	CDD:349493	74/75 (99%)
Smarcd1	NP_114030.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..128		125/126 (99%)
		Interaction with ESR1, NR1H4, NR3C1, PGR and SMARCA4. /evidence=ECO:0000250	43..167		123/123 (100%)
		Interaction with SMARCC1 and SMARCC2. /evidence=ECO:0000250	168..474		303/305 (99%)
		Necessary for GR/NR3C1-mediated remodeling and transcription from chromatin, required for GR/NR3C1 interaction with the BRG1/SMARCA4 complex in vivo. /evidence=ECO:0000250	180..515		332/334 (99%)
		SWIB_BAF60A	294..370	CDD:349493	74/75 (99%)