Protein Alignment SMARCC2 and ssr2

DIOPT Version :10

• Sequence 1: NP_001317217.1
• Gene: SMARCC2 / 6601
• HGNCID: 11105
• Length: 1245
• Species: Homo sapiens
• Sequence 2: NP_593800.1
• Gene: ssr2 / 2541851
• PomBaseID: SPAC23H3.10
• Length: 503
• Species: Schizosaccharomyces pombe
• Alignment Length: 593
• Identity: 185/593 - (31%)
• Similarity: 263/593 - (44%)
• Gaps: 196/593 - (33%)

Human   405 EQTKNPDLHEDNVTEQTHHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFM 469
            :|.:.|.|     .|||:.||:||||.|||.:.:|.||||:.|||||||:..|||.||..||:||
pombe     4 DQVRIPFL-----VEQTYPIIVPSYAGWFDMSKIHDIERRSNPEFFNGKSPLKTPSIYKDYRDFM 63

Human   470 IDTYRLNPQEYLTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVL 534
            |::|||.|.||||.|||||||.||||||:|||||||||||||||:|.|:||....||.:.|...:
pombe    64 INSYRLEPNEYLTVTACRRNLVGDVCAIIRVHAFLEQWGLINYQIDPETRPAFRLPPISGHVQAI 128

Human   535 ADTPSGLVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPEL----QTSASQQMLNFPDK 595
            ::||.....:..:.|     ...|..|...:|...|  |.....|.|    |||..::    .:|
pombe   129 SNTPIVTQEMLAQHP-----PPSTVGGSSSQEFVKL--EEKHYSPSLNAMEQTSPKEE----DEK 182

Human   596 GKEKP-TDMQNF--GLRTDMYTKKNVPSK--------------SKAAASA--------------T 629
            ..:.| .|...|  |:........|:.:|              |.:..|:              .
pombe   183 SDKVPRVDKVCFTCGVNCSQTWYHNLKNKKYDICPNCYKQGRFSSSFNSSDFLCMDAIDFNHDEE 247

Human   630 REWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLEDSEASLGPLAYQP 694
            :.|:.|||||||||:|.|.||||:::.||||||:::|::|||::||||||.:..:....|.....
pombe   248 KPWSNQETLLLLEAIETYGDDWNQIALHVGSRTKEQCLIHFLQIPIEDPYRQKLQGDFSPFKKGF 312

Human   695 IPFSQSGNPVMSTVAFLASVVDPRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGK 759
            :||.::.|||:||:.:|||:|
pombe   313 LPFDENENPVLSTLTYLASIV-------------------------------------------- 333

Human   760 ADPAFGLESSGIAGTTSDEPERIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEA 824
                                                                  ::..||:
pombe   334 ------------------------------------------------------QQGMKER---- 340

Human   825 PKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNL 889
                    |:.:|.|:.|.|.|:                          .|.|..:||
pombe   341 --------KQNESVKQGETSFGN--------------------------SEFKNPLER------- 364

Human   890 STAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQ 954
              .|..||.:||.|||.:||.|.|:::.||..|::.|::||::|::..|:||.:...|...|:.:
pombe   365 --VAYYALKSAAQKAKLIAAFENRQLRRLVFSLIQAQLEKLQLKMKVLEQLEKMCSLELSELDLR 427

Human   955 RQQLLADR 962
            .:.||..|
pombe   428 GKNLLLSR 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMARCC2	NP_001317217.1	SWIRM-assoc_2	4..420	CDD:465143	3/14 (21%)
		RSC8	379..>739	CDD:227584	146/368 (40%)
		SWIRM-assoc_3	715..781	CDD:465145	1/65 (2%)
		PTZ00121	<721..978	CDD:173412	39/242 (16%)
		SWIRM-assoc_1	<911..977	CDD:465142	17/52 (33%)
		PHA03247	<999..1234	CDD:223021
ssr2	NP_593800.1	RSC8	1..503	CDD:227584	185/593 (31%)