Protein Alignment SMARCC1 and smarcc1

DIOPT Version :10

• Sequence 1: NP_003065.3
• Gene: SMARCC1 / 6599
• HGNCID: 11104
• Length: 1105
• Species: Homo sapiens
• Sequence 2: XP_002942764.3
• Gene: smarcc1 / 100188924
• XenbaseID: XB-GENE-5906750
• Length: 1270
• Species: Xenopus tropicalis
• Alignment Length: 1113
• Identity: 848/1113 - (76%)
• Similarity: 945/1113 - (84%)
• Gaps: 51/1113 - (4%)

Human     4 AAGGGGPGTAVGATGSGIAAAAAGLAVYRRKDGGPATKFWESPETVSQLDSVRVWLGKHYKKYVH 68
            |||||                |:.|::.|:||||||:||||||||||||||||.|:||||||||.
 Frog   124 AAGGG----------------ASALSLARKKDGGPASKFWESPETVSQLDSVRAWIGKHYKKYVQ 172

Human    69 ADAPTNKTLAGLVVQLLQFQEDAFGKHVTNPAFTKLPAKCFMDFKAGGALCHILGAAYKYKNEQG 133
            ||:||||.||.||.|||||||||||:|||||||||||.|||||||||||||||||||||::::||
 Frog   173 ADSPTNKALAVLVSQLLQFQEDAFGRHVTNPAFTKLPVKCFMDFKAGGALCHILGAAYKHRSDQG 237

Human   134 WRRFDLQNPSRMDRNVEMFMNIEKTLVQNNCLTRPNIYLIPDIDLKLANKLKDIIKRHQGTFTDE 198
            ||||||||||||||||||||.|||||:|||||:||.:||:|:|:||||||||||:|||||..|:|
 Frog   238 WRRFDLQNPSRMDRNVEMFMTIEKTLMQNNCLSRPTVYLVPEIELKLANKLKDIVKRHQGAVTEE 302

Human   199 KSKASHHIYPYSSSQDDEEWLRPVMRKEKQVLVHWGFYPDSYDTWVHSNDVDAEIEDPPIPEKPW 263
            |.|||||:||..:|.||:|||||||:|:|||.||||:||||||||:.::|:||::||.|||||||
 Frog   303 KLKASHHVYPIPTSLDDDEWLRPVMKKDKQVQVHWGYYPDSYDTWIPASDLDADVEDAPIPEKPW 367

Human   264 KVHVKWILDTDIFNEWMNEEDYEVDENRKPVSFRQRISTKNEEPVRSPERRDRKASANARKRKHS 328
            |||.||::|||:|||||||||||||||:|..:||||||.||||.||||||:::||..:|:|||.|
 Frog   368 KVHAKWVMDTDVFNEWMNEEDYEVDENKKVANFRQRISLKNEEAVRSPERKEKKAVGSAKKRKRS 432

Human   329 PSPPPPTPTESRKKSGKKGQASLYGKRRSQKEEDEQEDLTKDMEDPTPVPNIEEVVLPKNVNLKK 393
            ||||   ..||||||||||...||||||.|||:||||||||||||||||||:|||:||||||.||
 Frog   433 PSPP---AAESRKKSGKKGPGGLYGKRRGQKEDDEQEDLTKDMEDPTPVPNMEEVLLPKNVNPKK 494

Human   394 DSENTPVKGGTVADLDEQDEETVTAGGKEDEDPAKGDQSRSVDLGEDNVTEQTNHIIIPSYASWF 458
            |||:||||||.|||||||:||||.|.|||||||::|||||.:|.||||||||||||||||||:||
 Frog   495 DSEHTPVKGGVVADLDEQEEETVAASGKEDEDPSRGDQSRMMDNGEDNVTEQTNHIIIPSYAAWF 559

Human   459 DYNCIHVIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLTGDVCAVM 523
            |||.|||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||
 Frog   560 DYNSIHVIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLSGDVCAVM 624

Human   524 RVHAFLEQWGLVNYQVDPESRPMAMGPPPTPHFNVLADTPSGLVPLHLRSPQVPAAQQMLNFPEK 588
            |||||||||||||||||.:||||||||||||||||||||||||||||:|:||||.||||||||||
 Frog   625 RVHAFLEQWGLVNYQVDADSRPMAMGPPPTPHFNVLADTPSGLVPLHMRTPQVPPAQQMLNFPEK 689

Human   589 NKEKPVDLQNFGLRTDIYSKKTLAKSKGASAGREWTEQETLLLLEALEMYKDDWNKVSEHVGSRT 653
            .||||.|||||||||||||||||||||.|||||||||||||||||||||||||||||||||||||
 Frog   690 MKEKPTDLQNFGLRTDIYSKKTLAKSKAASAGREWTEQETLLLLEALEMYKDDWNKVSEHVGSRT 754

Human   654 QDECILHFLRLPIEDPYLENSDASLGPLAYQPVPFSQSGNPVMSTVAFLASVVDPRVASAAAKAA 718
            ||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||:||||||
 Frog   755 QDECILHFLRLPIEDPYLENSDSSLGPLAYQPVPFSQSGNPVMSTVAFLASVVDPRVAAAAAKAA 819

Human   719 LEEFSRVREEVPLELVEAHVKKVQEAARASGKVDPTYGLESSCIAGTGPDEPEKLE----GAEEE 779
            |||||||||||||||||||:|||||||:|.||||||:||||||||||||:||||.|    ..|||
 Frog   820 LEEFSRVREEVPLELVEAHIKKVQEAAKALGKVDPTFGLESSCIAGTGPEEPEKQEKPSDAPEEE 884

Human   780 KME---ADPDGQQPEKAENKVENETDEGDKAQDGENEKNSEKEQDSEVSEDTKSEEKETEENKEL 841
            |||   |:|..|:....|.|:|.|:| .:.::..|.|| ...|:|:|.::..|:.|::||: ||.
 Frog   885 KMETETAEPAQQEKVTNEVKIEKESD-AESSEKPEVEK-KPAEEDAEPADKEKAAEEDTED-KEN 946

Human   842 TDTCKERESDTGKKKVEHEISEGNVATAAAAALASAATKAKHLAAVEERKIKSLVALLVETQMKK 906
            ..|   :|:|..|||.|:::||.|||.||||||||||||||||||||||||||||||||||||||
 Frog   947 EST---KEADPAKKKAENDLSEANVAMAAAAALASAATKAKHLAAVEERKIKSLVALLVETQMKK 1008

Human   907 LEIKLRHFEELETIMDREKEALEQQRQQLLTERQNFHMEQLKYAELRARQQMEQQQHGQNPQQAH 971
            ||||||||||||||||||||||||||||||.||||||||||||||:|||||:||||  |..||.|
 Frog  1009 LEIKLRHFEELETIMDREKEALEQQRQQLLNERQNFHMEQLKYAEMRARQQLEQQQ--QQQQQQH 1071

Human   972 QH----SGGPGLAPLGAAGHPGMMPH--QQPPPYPLMHHQMPPPHPPQPGQIPGPGSMMPGQHMP 1030
            |:    |.||.:|.:||...||||.|  ||||||. :||||||||..||||:|||.|||.|..||
 Frog  1072 QNAQGGSAGPNMAHVGAPSLPGMMGHQPQQPPPYG-VHHQMPPPHTSQPGQMPGPSSMMTGPPMP 1135

Human  1031 GRMIPTVAANIHPSGSGPTPP-GMPPM-PGNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPP 1093
            |||:|.:   :.|||..|.|| ||..: ||:::..|.|: |||||||.|    |||...|.|..|
 Frog  1136 GRMMPNI---LPPSGPHPPPPSGMAALPPGSMMASRPPM-APNGMYPGP----PPPAAGAAGSSP 1192

Human  1094 PPAPGPPA 1101
            ...|..|:
 Frog  1193 YGRPDTPS 1200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMARCC1	NP_003065.3	MarR-like, BRCT and chromo domains module. /evidence=ECO:0000255|PROSITE-ProRule:PRU01376	28..302		216/273 (79%)
		SWIRM-assoc_2	32..445	CDD:465143	325/412 (79%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	296..439		109/142 (77%)
		RSC8	444..>710	CDD:227584	253/265 (95%)
		SWIRM-assoc_3	706..772	CDD:465145	59/65 (91%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	745..860		58/121 (48%)
		SWIRM-assoc_1	883..954	CDD:465142	68/70 (97%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	956..1028		47/77 (61%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1041..1105		28/63 (44%)
smarcc1	XP_002942764.3	SWIRM-assoc_2	136..546	CDD:465143	325/412 (79%)
		RSC8	508..>811	CDD:227584	282/302 (93%)
		SWIRM-assoc_3	807..873	CDD:465145	59/65 (91%)
		PTZ00121	<870..1057	CDD:173412	126/192 (66%)
		SWIRM-assoc_1	984..1056	CDD:465142	69/71 (97%)