Protein Alignment SMARCB1 and smarcb1

DIOPT Version :10

• Sequence 1: NP_001349806.1
• Gene: SMARCB1 / 6598
• HGNCID: 11103
• Length: 403
• Species: Homo sapiens
• Sequence 2: NP_001006819.1
• Gene: smarcb1 / 448543
• XenbaseID: XB-GENE-493598
• Length: 378
• Species: Xenopus tropicalis
• Alignment Length: 402
• Identity: 370/402 - (92%)
• Similarity: 375/402 - (93%)
• Gaps: 24/402 - (5%)

Human     2 MMMALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVAS 66
            |:|||||||||||||||||:|||:|||||||||||||||||||||||||||||||||||||||||
 Frog     1 MIMALSKTFGQKPVKFQLEEDGEYYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVAS 65

Human    67 SHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYLREQKAKRNSQW 131
            |||||.      |||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog    66 SHGKKY------HGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYLREQKAKRNSQW 124

Human   132 VPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLWCGCIAALTLRADSALVLHFDDHDPAVIHE 196
            |||||||||||||||||||||||||||||||||||   |               |||||||||||
 Frog   125 VPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPL---C---------------FDDHDPAVIHE 171

Human   197 NASQPEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLTFVPAIASAIRQ 261
            ||:|.|||||||||||||||||||||||||||||||||||:||||||||||||.|||||||||||
 Frog   172 NAAQSEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFAEILCDDLDLNPLAFVPAIASAIRQ 236

Human   262 QIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFV 326
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   237 QIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFV 301

Human   327 TTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTR 391
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   302 TTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTR 366

Human   392 RMRRLANTAPAW 403
            ||||||||||||
 Frog   367 RMRRLANTAPAW 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMARCB1	NP_001349806.1	WH_NTD_SMARCB1	9..107	CDD:411036	88/97 (91%)
		SNF5	199..381	CDD:428158	177/181 (98%)
smarcb1	NP_001006819.1	DNA-binding. /evidence=ECO:0000250|UniProtKB:Q12824	1..106		100/110 (91%)
		WH_NTD_SMARCB1	8..100	CDD:411036	88/97 (91%)
		SNF5	174..356	CDD:428158	177/181 (98%)