Protein Alignment SMARCB1 and Snr1

DIOPT Version :10

• Sequence 1: NP_001349806.1
• Gene: SMARCB1 / 6598
• HGNCID: 11103
• Length: 403
• Species: Homo sapiens
• Sequence 2: NP_730935.1
• Gene: Snr1 / 40657
• FlyBaseID: FBgn0011715
• Length: 370
• Species: Drosophila melanogaster
• Alignment Length: 404
• Identity: 254/404 - (62%)
• Similarity: 301/404 - (74%)
• Gaps: 38/404 - (9%)

Human     4 MALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIV---A 65
            ||| :|:|.|||.||||:.||:|.:|||||||:|.|||.|||:||.:.|.:.:.||||::.   .
  Fly     1 MAL-QTYGDKPVAFQLEEGGEYYYVGSEVGNYMRHFRGILYKKYPGMTRIVLSNEERKRLAESGL 64

Human    66 SSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYLREQKAKRNSQ 130
            |||              .||:||:||:|.||::|:.||||||:|||::|......||.|:|:..|
  Fly    65 SSH--------------ILASSVSLLRAVEVDDIMAGNDEKYRAVSVNTSDTPVPRESKSKKQPQ 115

Human   131 WVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLWCGCIAALTLRADSALVLHFDDHDPAVIH 195
            :|||:|||| ||||||.:|.|||||:...|.||||:   |               |||.||....
  Fly   116 YVPTMPNSS-HLDAVPQATPINRNRVHTKKVRTFPM---C---------------FDDTDPTASL 161

Human   196 ENASQPEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLTFVPAIASAIR 260
            |||:|.|.|||||||||::||||||.||||.||.::|||.|:|:||||||||||.||||||.|||
  Fly   162 ENAAQKECLVPIRLDMELEGQKLRDTFTWNKNESMITPEQFAEVLCDDLDLNPLPFVPAIAQAIR 226

Human   261 QQIESYPTD-SILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGE 324
            ||||::|.| .|||:..|||||:||||||||.|||||.|||||||.|:||:||:|||:|||||||
  Fly   227 QQIEAFPNDPPILEETCDQRVIVKLNIHVGNTSLVDQVEWDMSEKNNNPEEFAIKLCAELGLGGE 291

Human   325 FVTTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRN 389
            |||.||||||||||||.:||||||.||.|:::..||..|||.|.|.|||||||||||||||||||
  Fly   292 FVTAIAYSIRGQLSWHCRTYAFSEAPLSTIDVPFRNPSDADAWAPFLETLTDAEMEKKIRDQDRN 356

Human   390 TRRMRRLANTAPAW 403
            ||||||||||...|
  Fly   357 TRRMRRLANTTTGW 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMARCB1	NP_001349806.1	WH_NTD_SMARCB1	9..107	CDD:411036	50/100 (50%)
		SNF5	199..381	CDD:428158	136/182 (75%)
Snr1	NP_730935.1	WH_NTD_SMARCB1	5..92	CDD:411036	50/100 (50%)
		SNF5	165..348	CDD:428158	136/182 (75%)