Protein Alignment PHACTR4 and CG32264

DIOPT Version :10

• Sequence 1: NP_076412.3
• Gene: PHACTR4 / 65979
• HGNCID: 25793
• Length: 712
• Species: Homo sapiens
• Sequence 2: NP_728897.1
• Gene: CG32264 / 38438
• FlyBaseID: FBgn0052264
• Length: 1008
• Species: Drosophila melanogaster
• Alignment Length: 810
• Identity: 246/810 - (30%)
• Similarity: 347/810 - (42%)
• Gaps: 209/810 - (25%)

Human    30 DSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELVKRGVL 94
            :|:.:|..|||.:||||.|..|:.|||||||:||.|:||:..|:.||||||:|..|:|||::|:|
  Fly   281 NSLGSGTRTPPLERKSKLSALGRFFKPWKWRRKKKSEKFEAASKSLERKISVRANRDELVQKGIL 345

Human    95 LED------PEQGGE------DPGKPSDAMLKNG--HTTPIG------NARSSSPVQVEEEPVRL 139
            :.:      ||.|.|      :.|..::..|.|.  |...:.      ||.:.:|:....:....
  Fly   346 MPESPLGNIPEPGEESYYNNSNSGATANGSLLNSAVHNNSMSQANNSINATTGNPLISAAQQQLN 410

Human   140 ASLRKAI-----------PEEDLKKRL---GSTGSQPNSEAESVPENVP------------KPPL 178
            ..|..:|           |:..:...|   |..|...:|:..|:...||            :||
  Fly   411 QGLPNSISVQQFNGQNQNPQNSMANGLVGGGGGGGDGSSDTSSLSGGVPHSQSAPQQLGVGQPP- 474

Human   179 LPPKRPLSSSHEASEGQAKDATSSGGTARFIISTS------ITTAPAATTAATSLAKTVNL---- 233
             ||..||:..|:|...|.:.        ||.||.:      .|.|............|.|:
  Fly   475 -PPLTPLAQHHQALAQQLQQ--------RFAISNNNEPRKDKTDAQQQQHGGNGTISTPNIEQPT 530

Human   234 ---SVTPSPA---------------PRTLPAAPASTNTTATPSLTH-----------MVPAKQPP 269
               |:.|.|.               |.||  |.|:..|....::.:           ||......
  Fly   531 CQGSMLPPPGGGGHHQVDGSGKMERPNTL--AGANKLTRRGVNICYHNEHMYGEDGKMVGGPPGS 593

Human   270 IPPPKPAHRNSNPVIAELSQAINSGTLLSK-PSPPLPPKRGIPSTSVPTLESAAAITTKTPSDER 333
            .|||.|..:            :..|.:||: |.||:|
  Fly   594 TPPPYPGGK------------LPPGVMLSELPEPPIP---------------------------- 618

Human   334 EKSTCSMGSELLPMISPRSPSPPLPTHIPPEP------PRTPPFPAKTFQVVPEIEFPPSLDLHQ 392
                          :|...|.||.|....|.|      |..|       ..|.:.::....|...
  Fly   619 --------------LSEIGPIPPPPMFSTPSPTLIAGRPHGP-------GAVNDQDYQQDYDYDD 662

Human   393 EIPQQEDQKKE---VP-----KRILDQNFGEPHIPSRLP---PLPLHIRIQ-----QALTSPLPM 441
            ..|.|::...:   .|     .|::|....| .||::.|   .:||...::     |..::..|:
  Fly   663 NDPDQDELDSDDEYAPYGGNHVRMMDTQRVE-EIPAKEPKPNAVPLKSALKKKGGMQPASASTPV 726

Human   442 TPILE---GSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEMLKVPDDEEEEE----------- 492
            ||..|   ||....:.:..::......::..............|.|..|.....
  Fly   727 TPTQEHGAGSAATAAAMANSNGGIGSMAAAAAAAAQQSANQRPLVVRQDAAGNNYSLKPILRPRI 791

Human   493 QTCPSTFSEEMTPTSVIPK---LPQCLREEEEKESDS-DSEGPIQYRDEEDEDESYQSALANKVK 553
            :.|.........|.:|..|   .|..:|   |..||| ||:|.|.||||::::    :.|| |:.
  Fly   792 RLCRQQMFNIQLPCTVENKENARPFVIR---ESSSDSDDSDGHIVYRDEDNDN----TRLA-KLA 848

Human   554 RKDTLAMKLNHRPSEPEL-NLNSWPCKSKEEWNEIRHQIGNTLIRRLSQRPTPEELEQRNILQPK 617
            ||::|::||..||.:.:| |.|.....:..|..|.:..||..||||||.|||.|||.:||||:.:
  Fly   849 RKESLSLKLQLRPDKQDLINRNILHQVNDNELKESKEAIGARLIRRLSMRPTAEELVERNILKTQ 913

Human   618 NEADRQAEKREIKRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAQDYDRRADKPWTKLTPADK 682
            :.|:.:.:|.|.|..|.||||.||||.||..:||:|||:|:|||.|.|||||||||||:|||.||
  Fly   914 SPAEEKKQKEEKKSYLLRKLSFRPTVEELKEKKIIRFNDYIEVTQAHDYDRRADKPWTRLTPKDK 978

Human   683 AAIRKELNEFKSSEMEVHEESKHFTRYHRP 712
            |||||||||||||||.|||.|:|.||:|||
  Fly   979 AAIRKELNEFKSSEMAVHEGSRHLTRFHRP 1008

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHACTR4	NP_076412.3	RPEL	75..97	CDD:460677	13/21 (62%)
		RPEL	594..618	CDD:128947	16/23 (70%)
		RPEL	631..656	CDD:128947	15/24 (63%)
CG32264	NP_728897.1	RPEL	325..348	CDD:460677	13/22 (59%)
		RPEL	851..876	CDD:128947	8/24 (33%)
		RPEL	889..914	CDD:128947	16/24 (67%)
		RPEL	927..952	CDD:128947	15/24 (63%)