|
Human 49 PPSAGHPIPTQ-GPGGYPQD-NMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPS 111
|..||..:..| |.|...|: .:.::...:.||.|:|:.:|.|
Worm 15 PQPAGEVVAQQAGDGAQGQELTISKLENAITSMEEQGLQNDHR---------------------- 57
Human 112 PMDQHSQGYPSPLGGSEHASSPVPASGPSSGPQMSSG-PGGAPLDGADPQALGQQNRGPTPFNQN 175
||.:.:... ::.|| |...| ||:|.|.......
Worm 58 -----------------HAKAVLLKQ------KLQSGLPDAVP---------GQENGGNQQITPA 90
Human 176 QLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP 240
||:|||||:.||::|||.:.:|.:|.......|| ::.||.
Worm 91 QLNQLRAQVSAYRLLARNEQVPANLIADAVMLRP------KVTTLL------------------- 130
Human 241 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPP 305
|.|..| ||:...|...|:....:.|
Worm 131 ---PEPYEY-----------------------PGEAENGEKLPYDLMKIFN-------------- 155
Human 306 QPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQ-KQSRITPIQKPRGLDPVEILQE 369
||| :.:|.|.|..|.|:|||.:|::
Worm 156 ---------------------------------------LHQIRCNRPTTISVPSGIDPVGMLKQ 181
Human 370 REYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEVVVCMRRDTALETAL 434
||..:|.||..|::.|.|||..:...::.||.|||:||||:|.|.|:|.||:.|::|||.|||||
Worm 182 RENMIQNRIGLRMKLLNNLPADIPDHMKLKAEIELRALRLVNLQTQVRSEVMACLKRDTTLETAL 246
Human 435 NAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVTGKIQK 499
|..||:|:|||||||||:|||||||||:||||||||||.:.:.:|:||.|:||||||:...|:.|
Worm 247 NPYAYRRTKRQSLREARVTEKLEKQQKMEQERKRRQKHTDLMQAIIQHGKEFKEYHRNNLLKMAK 311
Human 500 LTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAYLLQQTDEYVANL 564
..|||.|||.|.|||:||:..|.||.||::||.|||||||.|:|:|||:||.||||||||||.:|
Worm 312 SRKAVMTYHQNNERERKKDEIRNEKLRMQKLMQEDEEGYRALLDEKKDQRLVYLLQQTDEYVDSL 376
Human 565 TELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHV---ESGK 626
..|||||:.. ||||||:.||.|. |..:||.:: :|| .:||
Worm 377 CSLVRQHQNT----EKKKKKEDKKIEK-----------GNQMDEEAR--------VHVRERSTGK 418
Human 627 ILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIP 691
.|||..|||..::|.|||.:|.||:.|| :..|::||||||| .||| |
Worm 419 ALTGDQAPKTEEIEFWLETHPEYEIVPR----DQLSDDEEEEEEE----------APVE-----P 464
Human 692 DPDSDDV-----SEVDARHIIENAKQDVDDEYGVSQALARGLQSYYAVAHAVTERVDKQSALMVN 751
:.:.||. .|..|:.|:|.|:.: :||| .|...:.:..|||.||.:.|:|.||...|..
Worm 465 EEEKDDQYAGMDEETKAKMILEKARNE-EDEY--DQKTKKQMADYYATAHKIKEKVVKQHTTMGG 526
Human 752 G----VLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPL 812
| :||.||||||||:|||||||||||||||||||||||||:|:|||||.|:.|||:|:||||
Worm 527 GDPNLLLKPYQIKGLEWMVSLYNNNLNGILADEMGLGKTIQTISLVTYLMEVKQNNGPYLVIVPL 591
Human 813 STLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKY 877
||||||..||.||||||..:.|||:..|||....|:|.|.||||:|||||:||:|.:|.||||||
Worm 592 STLSNWQNEFAKWAPSVTTIIYKGTKDARRRVEGQIRKGAFNVLMTTYEYVIKEKALLGKIRWKY 656
Human 878 MIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQW 942
||:|||||:|||:||||.:||..:.|..|||||||||||||||||||||||||:||.||.|||||
Worm 657 MIIDEGHRLKNHNCKLTLMLNGFFHAQHRLLLTGTPLQNKLPELWALLNFLLPSIFSSCGTFEQW 721
Human 943 FNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVL 1007
||||||.|||||:||:|||:|||||||||||||||||||||||:|||:|.|||||||.||||:|:
Worm 722 FNAPFATTGEKVELNQEETMLIIRRLHKVLRPFLLRRLKKEVESQLPDKTEYVIKCDQSALQKVI 786
Human 1008 YRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQG 1072
||||| ||:|| |.|...|.::||||::.|||:||||::|.:||:|...: :....|.|
Worm 787 YRHMQ-KGLLL------DAKMSSGARSLMNTVVHLRKLCNHPFLFPNIEDSCRAY--WKVNEVNG 842
Human 1073 LDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGM 1137
.||.|.:||.||||||||||:||.|::|:|.||||:|.|.||:..:|.:.||||||:||.::||.
Worm 843 TDLMRVAGKLELLDRILPKLKATGHRILMFFQMTSMMNIFEDFLNFRRYTYLRLDGSTKPDERGD 907
Human 1138 LLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVL 1202
||..||.|.|:.|:|:|||||||||||||:||||||||||||||||:|||||||||||:.|||||
Worm 908 LLTQFNAPNSDLFLFMLSTRAGGLGLNLQTADTVIIFDSDWNPHQDMQAQDRAHRIGQKKEVRVL 972
Human 1203 RLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSG 1267
||.|.|||||||||||:||||||:||||||.|||:|:..||:..|:.|::.:.::|
Worm 973 RLITANSVEEKILAAARYKLNVDEKVIQAGKFDQRSTGAERKQMLEQIIQADGEEE--------- 1028
Human 1268 SASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPK 1332
||:|||||||||||:||.||||::|..||:|||||||....
Worm 1029 ------------------------EEEEVPDDETVNQMVARSEEEFNIFQSMDIDRRREEANQLH 1069
Human 1333 RKPRLMEEDELPSWIIK---DDAEVERLTCEEEEEKMFGR---GSRHRKEVDY-SDSLTEKQWLK 1390
|||||:||.|:|..|:| |..|:|| ..||..::..: ..|.|:|||| ||.|:::|::|
Worm 1070 RKPRLLEEHEIPDDILKLSFDYEEMER--AREEGREVVDQTPNQRRRRREVDYSSDLLSDEQFMK 1132
Human 1391 KITGKDIHDTASSVARGLQFQRGLQFCTRASKAIEEGTLEEIEEE----VRQKKSSRKRKRDSDA 1451
:: ||:|:| |.::|..||||. |
Worm 1133 QV-------------------------------------EEVEDENNQAVAERKKQRKRKM---A 1157
Human 1452 GSSTPTTSTRSRDKDDES-------KKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSS 1509
| .|::|:| .|:|| ..|.|.:|:.:::|.:::|| :..
Worm 1158 G----------LDENDDSMDDVVLQHKKKK-----------TDPELAEKINEMLDVILEYK-NED 1200
Human 1510 GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLE 1574
|..:::||..||:|||||:||::|.||:||.:|.::|...:|..:.:|..|:.||..||||:|.|
Worm 1201 GELIADVFQTLPTRKELPDYYQVISKPMDFDRINKKIETGRYTVMEELNDDMNLLVNNAQTYNEE 1265
Human 1575 GSLIYEDSIV------------------------------------------------------- 1584
||.||..|..
Worm 1266 GSEIYVSSETIGKLWKEQYDKFMNPPKPVEEPVKKKEPSTPSTSSSRPSTSGTPSVSDLQRTQQA 1330
Human 1585 -----------------------------------------LQSVFTSVR---------QKIEKE 1599
:||...:.| :|.||:
Worm 1331 TAQQMLMLMTHMQSLPPAQAQQFQQALMTQTGGNQALMLQYMQSAMLAQRAQASTKVTPKKDEKK 1395
Human 1600 DDSEGEESEEEEEGEEEGSESESRSVKVKIKLGR------KEKAQDRLKGGRRRPS---RGSRAK 1655
:.|...::||.::.:|..:.|.|.....|.|... :|..::.:.|.::.|: |.||..
Worm 1396 ETSSSVKTEEAKKDDEPSTSSASAPPPKKKKESEDSEDPMEEDEEEEIIGQKKEPASSRRKSRPT 1460
Human 1656 PVVSDDDSEEEQEE 1669
...|::|.|||.:|
Worm 1461 RRFSNEDEEEEDDE 1474
| 
