Protein Alignment SLC22A2 and CG31103

DIOPT Version :9

• Sequence 1: NP_003049.2
• Gene: SLC22A2 / 6582
• HGNCID: 10966
• Length: 555
• Species: Homo sapiens
• Sequence 2: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 497
• Identity: 123/497 - (24%)
• Similarity: 192/497 - (38%)
• Gaps: 128/497 - (25%)

Human   108 ASLDTNRSRLPLGPCRDGWVYE-----------------TPGSSIVTEFN-------LVCANSWM 148
            :||::|    .|||  :.|.|:                 ..|...:|...       :|.|:...
  Fly     3 SSLESN----TLGP--NVWDYDMVLEKIGYGKTQWVLLLVSGLLTITSVAAQQAMSIIVIASQCE 61

Human   149 LDLFQSSVNV-------GFFIGSMSIGYIADRFGRKLCLL-TTVLINAAAGVLMAISPTYTWML- 204
            .:..|:...|       |.|:.:...|||:|..||:..|| .....||...|||.:  |..|:.
  Fly    62 FETTQAEKGVMMAASVTGIFLSTYIWGYISDDIGRRRVLLYGNFASNALQFVLMFV--TSVWLFN 124

Human   205 IFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIFYQVAY----------TVGLLVLAGVA--- 256
            |..|:.|:...|.....|..::||...|: |.|.|.|...:          |..|::.:..|
  Fly   125 IINLLVGISVGAVSAALYAYLSEFNIPRH-RAVAINYSTMFVSVTAIYVPATAWLVLSSNWAITM 188

Human   257 --YALPHWRWLQFTVSLPNF---FFLLYYWCIPESPRWLISQNKNAEAMRIIKHIAKKN-GKSLP 315
              :....||.|.....||.|   ..||||   ||||::|:||.||.||:..:..|:|.| |||:.
  Fly   189 GDFVFRPWRLLLLVSLLPGFIGGLILLYY---PESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQ 250

Human   316 ASLQRLRLEEETGKKLNPSFLDLVRTPQ-------IRKHTMILM-----YNWFTSSVLYQGLIM- 367
               |.|..:|.|.|..:|...:|:...|       |.:.|:.|.     :|:...::...|:..
  Fly   251 ---QVLSCDEFTLKSEDPVGENLLGESQGCGILSKICRATIPLFHKPHGFNFILCNLALFGMFFS 312

Human   368 --------------HMGLAGDNIYLDFFYSALVEFPAAFMIILTIDRI-GRRYPWAASNMVAGAA 417
                          ..|...::..:....|..||.|.....:...|.| .:.|   ..|:|.|.|
  Fly   313 SNGMQLWFPEIVNRSSGAENNSSTVCEILSVPVEQPNVTETLDCTDPISSKTY---IDNLVVGFA 374

Human   418 CLASVFIPGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYPTFIRNLGVHICSSMCDIGGIITP 482
            .|....|.|      :|::.|||..:.:|...|..::..|         :|...|..   |::..
  Fly   375 FLIGFSIQG------LILNPLGRKNVLLAALAVATLSGVL---------LHFMESPT---GVLVL 421

Human   483 FLVYRLTNIWLELPLMVFGV-LGLVAGGLVLLLP-ETKGKAL 522
            |.:|.|      ||    |: :.::.|.:|.|:| ..:.||:
  Fly   422 FCLYIL------LP----GLSISIMIGAIVDLVPTHLRSKAV 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A2	NP_003049.2	2A0119	13..525	CDD:273328	123/497 (25%)
		MFS	124..492	CDD:119392	108/447 (24%)
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	115/465 (25%)
		MFS	34..>189	CDD:119392	38/157 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153348
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840