Protein Alignment SLC22A2 and CG7333

DIOPT Version :9

• Sequence 1: NP_003049.2
• Gene: SLC22A2 / 6582
• HGNCID: 10966
• Length: 555
• Species: Homo sapiens
• Sequence 2: NP_650814.2
• Gene: CG7333 / 42334
• FlyBaseID: FBgn0038715
• Length: 541
• Species: Drosophila melanogaster
• Alignment Length: 547
• Identity: 147/547 - (26%)
• Similarity: 238/547 - (43%)
• Gaps: 61/547 - (11%)

Human     8 VLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHRCRSPGVAELSLRCGWSPAEELN 72
            ||:..|.:..||..:..|....:...:..|.....:.|||:|.|....:..||:....|..|.::
  Fly     6 VLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHADLNGLSVEGIRSVYENIS 70

Human    73 YTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVDPLASLDTNRSRLPLGPCRDGWVY--ETPGSSI 135
                    |...:|             ....|:....:.|||.      ||: |::  |:...||
  Fly    71 --------ASSCTP-------------LLGVVNGTGVVSTNRK------CRN-WIFNRESGYESI 107

Human   136 VTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAISPTY 200
            .||...||..|....:.||...:|..:|::..||::|:.||...||...|..|....:.:...|.
  Fly   108 TTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHTL 172

Human   201 TWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVG--IFYQVAYTVGLLVLAGVAYALPHWR 263
            .|....|.:.||.:...:.:.|||:.|::..: .||.|  |...|.|..||:.....|..:.:||
  Fly   173 PWFAFSRFMSGLSTDTMYYLMYILVFEYLSPK-SRTFGLNIILAVFYCFGLMTSPWAAIWIGNWR 236

Human   264 WLQFTVSLPNFFFLLYYWCIPESPRWLISQNKNAEAMRIIKHIAKKNGKSLPAS-----LQRLRL 323
            ...:..|||....|:|.:.|.||.:||:::.|..:|:..:|.:||.|.:.:..|     ::..|.
  Fly   237 RYLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVKYYRE 301

Human   324 EEETGKKLN---PSFLDLVRTPQIRKHTMILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSAL 385
            .|....|||   .:||.:..||::|:.|:.|:......::....:..:|...|.:.:..|.::::
  Fly   302 RELQDYKLNSHEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTSPFKLFSFTSI 366

Human   386 VEFPAAFMIILTIDRIGRRYPWAASNMVAGAACLASVFI-----PGDLQWLKIIISCLGRMGITM 445
            |..||...|:|..::|||:.....:..|.|....|:.|:     |.:...|..|:..|||.|.|:
  Fly   367 VYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATGFMIAHLDPTENALLLAIMVGLGRFGATV 431

Human   446 AYEIVCLVNAELYPTFIRNLGV---HI----CSSMCDIGGIITPFLVYRLTNIWLELPLMVFGVL 503
            :|:......||:.||.:|...|   |:    .||:.        |.|..|...:..||.:....|
  Fly   432 SYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLA--------FYVIYLAQYYKPLPSIFISCL 488

Human   504 GLVAGGLVLLLPETKGKALPETIEEAE 530
            .....||.|.||||..|.||||:.:.|
  Fly   489 MFFGAGLCLTLPETLNKKLPETLADGE 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A2	NP_003049.2	2A0119	13..525	CDD:273328	142/535 (27%)
		MFS	124..492	CDD:119392	107/391 (27%)
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	142/535 (27%)
		MFS	126..499	CDD:119392	103/381 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153654
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950