Protein Alignment SLC22A2 and CG31272

DIOPT Version :9

• Sequence 1: NP_003049.2
• Gene: SLC22A2 / 6582
• HGNCID: 10966
• Length: 555
• Species: Homo sapiens
• Sequence 2: NP_650013.3
• Gene: CG31272 / 326130
• FlyBaseID: FBgn0051272
• Length: 563
• Species: Drosophila melanogaster
• Alignment Length: 482
• Identity: 100/482 - (20%)
• Similarity: 193/482 - (40%)
• Gaps: 115/482 - (23%)

Human   121 PCRDGWVYETPGSSIV-----TEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCL 180
            |.:...::|:...|.:     .:..|...:..:|:   :....|..|.:::.||:||..|||..|
  Fly    67 PAQSAAIFESSSMSYILPIAECDLRLTLEDKGVLN---AVAYAGMTISAIAWGYLADTKGRKKIL 128

Human   181 LTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRT----VGIFY 241
            ....||:|......|:|..::.:::|:.:.|||......:.:..:||..|.::|.:    ||:..
  Fly   129 YWGYLIDAVCVFGSALSQNFSMLVMFKFLGGLVVNGPAAVLFTYLTEMHGPKHRSSVLMIVGMVT 193

Human   242 QVAYTVGLLVLA-GV----------AYALPHWRWLQFTVSLPNFFFLLYYWCIPESPRWLISQNK 295
            ..| ||.|.:|| |:          ...:..|:...|.:.:|:....|.:..:|||||:|::|.:
  Fly   194 STA-TVSLPLLAWGIFPRDWDFEFWGLQVHSWQIFLFVLGIPSLISGLIFCSMPESPRFLMAQGR 257

Human   296 NAEAMRIIKHI----AKKNGKSLP--ASLQRL------------RLEEETG----KKLNPSFLDL 338
            |.||::..|.|    .:|...|.|  |.:|.:            .:||::|    |:.:.:..:.
  Fly   258 NEEALQAFKQIYHVNTRKPKDSYPIKALIQEVPNRKAAQNEVIYTIEEKSGEVPTKRQSRTLAES 322

Human   339 VRT------PQIRKHTM-------ILMYN----------W----FTSSVLYQGLIMHMGLAGDNI 376
            :|.      |.:||..:       ::.:.          |    |.|...|:.|  |   |||.
  Fly   323 LRAGLQQMKPLVRKPLLGLAICCYVMQFGIFLGMNTIRLWLPQLFASMAEYEAL--H---AGDG- 381

Human   377 YLDFFYSALVEFPAAFMIILTIDRIGR---RYPWAAS------------NMVAGAACLASVFIPG 426
             ||.....::||        ::::...   .|..|.|            |::..|......|..|
  Fly   382 -LDVSMCTILEF--------SVNQTAETALNYADACSEPKVISMDMYLNNIIVSATGFVGYFFAG 437

Human   427 DL-------QWLKIIISCLGRMGITMAYEIVCLVNAELYPTFIRNLGVHICSSMCDIGGIITPFL 484
            .:       :.:...:...|..|:.:.:.:..|:...:..||:...|:.:.|.:    |.:....
  Fly   438 GILRALGPKRMMTYGLFLSGTFGLMLYFSVSSLMTLIVSATFLTITGIAVSSLL----GAVVALF 498

Human   485 VYRLTNIWLELPLMVFGVLGLVAGGLV 511
            ..:|..:.:.:.:|. |..|.::|.|:
  Fly   499 PTQLRTVVVAIAMMC-GRFGALSGNLL 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A2	NP_003049.2	2A0119	13..525	CDD:273328	100/482 (21%)
		MFS	124..492	CDD:119392	94/458 (21%)
CG31272	NP_650013.3	MFS	62..555	CDD:119392	100/482 (21%)
		2A0115	74..524	CDD:273327	98/473 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153565
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840