Protein Alignment SLC22A2 and CG15221

DIOPT Version :9

• Sequence 1: NP_003049.2
• Gene: SLC22A2 / 6582
• HGNCID: 10966
• Length: 555
• Species: Homo sapiens
• Sequence 2: NP_001096957.1
• Gene: CG15221 / 32127
• FlyBaseID: FBgn0030331
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 509
• Identity: 114/509 - (22%)
• Similarity: 205/509 - (40%)
• Gaps: 117/509 - (22%)

Human   120 GPCRDGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVN----------VGFFIGSMSIGYIADRF 174
            |.|..|.:.|..|.|::       .|....|| |.::|          :|..:.|.::|::||.:
  Fly    55 GLCFMGVMVEIMGVSLI-------MNQMKCDL-QPTLNQQGILASAGFLGVVLSSHAMGFLADTW 111

Human   175 GRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEF--VGRRYRRT- 236
            ||...|...:.|::...::.|.|.....:::||.:.|.....|....:.|..||  .|.|.|..
  Fly   112 GRATTLRYALCISSVCSIVSAFSVNIWMLIVFRFLTGFFISGGQACVFSLCGEFHGTGSRIRHVT 176

Human   237 -------VGIFYQVAYTVGLL------VLAGVAYALPHWRWLQF-TVSLPNFFFLLYYWCIPESP 287
                   :.:.:..|..:|:|      ::.|:.::  .||.|.. .||:| ...|:....:||:|
  Fly   177 LLSGFLCMAMIFAPAMAIGILPLRIETIVLGMHFS--SWRVLLLANVSIP-LLALVGISALPETP 238

Human   288 RWLISQNKNAEAMRIIKHIAKKNGKSLPAS--LQRLRLEEETGKKLNP--SFLDLVRTPQIRKHT 348
            ::|:.|.:..|::.:::.|...|....|:.  ::.:.| |..|..|:.  .|||.||.  :...|
  Fly   239 KYLLVQGRGDESLEVLRSIFANNSGRDPSEYPVKEVAL-ESGGVSLSDVHGFLDAVRL--VWHQT 300

Human   349 MILMYN---WFTSSV---------LYQGLIM-------HMGLA-GDNIYL--------------- 378
            :.|.|.   |.|.::         |.||:.|       .:|.. |:|..|
  Fly   301 VPLFYRARLWHTLNICCIQFIIYFLAQGIFMWFPTILDELGTRNGENTLLCTVLQGFNINSSSED 365

Human   379 ----------DFFYSALVEFPAAFMII-----LTIDRIGRR---YPWAASNMVAGAACLASV-FI 424
                      ...|..::...|.|::|     ..||.:|::   ..|....|:    ||.:: ::
  Fly   366 EASSCSVEVDTSTYQVMIIIAACFVVIYLIFAYIIDYMGKKNLLMAWMVLTMI----CLVALHYV 426

Human   425 PGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYPTFIRNLGVHICSSMCDIGGIITPFLVYRLT 489
            .   |:..::|:....|.|.....:|..:..|.|||.|..:|:.....:..:|.::...::.||
  Fly   427 E---QFALVVIALTVVMAIGNCGGLVSTIAMEFYPTHINAMGMCFIMMVGRLGAVVGSNILGRL- 487

Human   490 NIWLELPLMVFGVLGLVAGGLVLLLPETKGKALPETIEEAENMQRPRKNKEKMI 543
             ::.....:.:.:|.||    |||.  |.|..||   |:|.:.|:......|.|
  Fly   488 -LFASCDPIFWALLALV----VLLC--TLGYFLP---EKARSQQKKPSATAKAI 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A2	NP_003049.2	2A0119	13..525	CDD:273328	109/489 (22%)
		MFS	124..492	CDD:119392	97/452 (21%)
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	99/455 (22%)
		MFS	51..488	CDD:119392	99/455 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153350
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840